PDF(Pubmed)
Abstract：
UNASSIGNED: The use of herbal medicines (HMs) for the treatment of hypertension (HTN) is increasing globally, but research on the potential adverse effects and safety of HMs in HTN patients is limited. Therefore, this systematic review and meta-analysis aim to determine the global prevalence of HM usage among HTN patients and assess the safety of identified herbs based on current scientific evidence.
UNASSIGNED: The PubMed/MEDLINE, EMBASE (Ovid), and Cumulated Index to Nursing and Allied Health Literature (CINAHL) databases were searched for cross-sectional studies on the use of HM among HTN patients. Our review includes studies published in English up to the year 2023. After extracting and appraising the data from the studies, a meta-analysis was conducted using the Stata version 16.0 to estimate the pooled prevalence of HM use in patients with HTN (PROSPERO: CRD42023405537). The safety classification of the identified HM was done based on the existing scientific literature.
UNASSIGNED: This study analyzed 37 cross-sectional studies from 21 countries and found that 37.8% of HTN patients used HM to manage their health. The prevalence of HM use varied significantly based on publication year and geographical region. Among the 71 identified herbs, Allium sativum L., Hibiscus sabdariffa L., and Olea europaea L. were the most commonly used. However, four herbs were identified as contraindicated, 50 herbs required caution, and only 11 herbs were considered safe for use.
UNASSIGNED: The study highlights the potential risks of toxicities and adverse effects associated with HM use in the treatment of HTN. Ensuring patient safety involves using safe HMs in appropriate doses and avoiding contraindicated HMs. Future research should focus on identifying commonly used herbs, especially in resource-limited countries with poor HTN management, and additional clinical research is required to assess the toxicity and safety of commonly used HMs.
UNASSIGNED: The PubMed/MEDLINE, EMBASE (Ovid), and Cumulated Index to Nursing and Allied Health Literature (CINAHL) databases were searched for cross-sectional studies on the use of HM among HTN patients. Our review includes studies published in English up to the year 2023. After extracting and appraising the data from the studies, a meta-analysis was conducted using the Stata version 16.0 to estimate the pooled prevalence of HM use in patients with HTN (PROSPERO: CRD42023405537). The safety classification of the identified HM was done based on the existing scientific literature.
UNASSIGNED: This study analyzed 37 cross-sectional studies from 21 countries and found that 37.8% of HTN patients used HM to manage their health. The prevalence of HM use varied significantly based on publication year and geographical region. Among the 71 identified herbs, Allium sativum L., Hibiscus sabdariffa L., and Olea europaea L. were the most commonly used. However, four herbs were identified as contraindicated, 50 herbs required caution, and only 11 herbs were considered safe for use.
UNASSIGNED: The study highlights the potential risks of toxicities and adverse effects associated with HM use in the treatment of HTN. Ensuring patient safety involves using safe HMs in appropriate doses and avoiding contraindicated HMs. Future research should focus on identifying commonly used herbs, especially in resource-limited countries with poor HTN management, and additional clinical research is required to assess the toxicity and safety of commonly used HMs.
摘要：
■在全球范围内，治疗高血压（HTN）的草药（HM）的使用正在增加，但是关于HMs在HTN患者中的潜在不良反应和安全性的研究有限.因此,本系统综述和荟萃分析旨在确定HTN患者中HM使用的全球患病率,并根据现有科学证据评估已确定草药的安全性.
■PubMed/MEDLINE,EMBASE(Ovid),并搜索了护理和相关健康文献（CINAHL）累积索引数据库，以进行HTN患者中HM使用的横断面研究。我们的评论包括直到2023年以英语发表的研究。在从研究中提取和评估数据后，使用Stata16.0版进行荟萃分析,以估计HTN患者使用HM的合并患病率(PROSPERO:CRD42023405537).基于现有的科学文献对鉴定的HM进行安全分类。
■这项研究分析了来自21个国家的37项横断面研究，发现37.8％的HTN患者使用HM来管理自己的健康。HM使用的患病率因出版年份和地理区域而异。在71种确定的草药中，大蒜L.,HibiscussabdarifaL.,OleaeuropaeaL.是最常用的。然而,四种草药被确定为禁忌，50草药需要谨慎，只有11种草药被认为是安全的。
■该研究强调了与HM治疗HTN相关的潜在毒性和不良反应风险。EnsuringpatientsafehMsinvolvesusingsafehMsinappropriatedosesandavoiding禁忌hMs.Futureresearchshouldfocusonidentifycommonlyusedhigrants,特别是在HTN管理不善的资源有限的国家，需要额外的临床研究来评估常用HMs的毒性和安全性。
■PubMed/MEDLINE,EMBASE(Ovid),并搜索了护理和相关健康文献（CINAHL）累积索引数据库，以进行HTN患者中HM使用的横断面研究。我们的评论包括直到2023年以英语发表的研究。在从研究中提取和评估数据后，使用Stata16.0版进行荟萃分析,以估计HTN患者使用HM的合并患病率(PROSPERO:CRD42023405537).基于现有的科学文献对鉴定的HM进行安全分类。
■这项研究分析了来自21个国家的37项横断面研究，发现37.8％的HTN患者使用HM来管理自己的健康。HM使用的患病率因出版年份和地理区域而异。在71种确定的草药中，大蒜L.,HibiscussabdarifaL.,OleaeuropaeaL.是最常用的。然而,四种草药被确定为禁忌，50草药需要谨慎，只有11种草药被认为是安全的。
■该研究强调了与HM治疗HTN相关的潜在毒性和不良反应风险。EnsuringpatientsafehMsinvolvesusingsafehMsinappropriatedosesandavoiding禁忌hMs.Futureresearchshouldfocusonidentifycommonlyusedhigrants,特别是在HTN管理不善的资源有限的国家，需要额外的临床研究来评估常用HMs的毒性和安全性。
