PDF(Pubmed)
Abstract：
UNASSIGNED: COVID-19 is an infectious pathology that shows vascular changes during pregnancy, as well as in the placentas. The main objectives of this study were to estimate the prevalence and the risk factors for preeclampsia in hospitalized pregnant women with COVID-19. As well as comparing maternal and perinatal outcomes in hospitalized pregnant women with COVID-19 and preeclampsia with those without preeclampsia.
UNASSIGNED: Prospective cohort study of 100 hospitalized pregnant women from two tertiary hospitals, diagnosed with COVID-19, and divided into two groups: PE+ group (pregnant women with COVID-19 and preeclampsia) and PE- group (pregnant women with COVID-19 without preeclampsia). These pregnant women had prevalence, risk factors, maternal and perinatal data analyzed.
UNASSIGNED: The prevalence of preeclampsia was 11%. Severe COVID-19 was the main risk factor for preeclampsia (OR = 8.18 [CI 1.53-43.52]), as well as fetal growth restriction was the main perinatal outcome (OR = 8.90 [CI 1.52-38.4]). Comorbidities were more frequent in the PE+ group (63.6% vs 31.5%, p = 0.03), as well as prematurity (81.8% vs 41.6%, p = 0.02), low birth weight (63.6% vs 24.7%, p = 0.01), and the need for neonatal intensive care admission of the newborn (63.6% vs 27.0%, p = 0.03). Pregnant women with PE had twice as long a length of stay in the intensive care unit (RR = 2.35 [CI 1.34-4.14]). Although maternal mortality was more frequent among pregnant women with PE, it was not statistically significant.
UNASSIGNED: Prevalence of preeclampsia in hospitalized pregnant women with COVID-19 was 11%. Severe COVID-19 was the main risk factor for preeclampsia and associated comorbidities increased the risk for developing preeclampsia. Long length of stay in the intensive care unit was the main maternal outcome and fetal growth restriction was the main perinatal outcome of preeclampsia.
UNASSIGNED: Prospective cohort study of 100 hospitalized pregnant women from two tertiary hospitals, diagnosed with COVID-19, and divided into two groups: PE+ group (pregnant women with COVID-19 and preeclampsia) and PE- group (pregnant women with COVID-19 without preeclampsia). These pregnant women had prevalence, risk factors, maternal and perinatal data analyzed.
UNASSIGNED: The prevalence of preeclampsia was 11%. Severe COVID-19 was the main risk factor for preeclampsia (OR = 8.18 [CI 1.53-43.52]), as well as fetal growth restriction was the main perinatal outcome (OR = 8.90 [CI 1.52-38.4]). Comorbidities were more frequent in the PE+ group (63.6% vs 31.5%, p = 0.03), as well as prematurity (81.8% vs 41.6%, p = 0.02), low birth weight (63.6% vs 24.7%, p = 0.01), and the need for neonatal intensive care admission of the newborn (63.6% vs 27.0%, p = 0.03). Pregnant women with PE had twice as long a length of stay in the intensive care unit (RR = 2.35 [CI 1.34-4.14]). Although maternal mortality was more frequent among pregnant women with PE, it was not statistically significant.
UNASSIGNED: Prevalence of preeclampsia in hospitalized pregnant women with COVID-19 was 11%. Severe COVID-19 was the main risk factor for preeclampsia and associated comorbidities increased the risk for developing preeclampsia. Long length of stay in the intensive care unit was the main maternal outcome and fetal growth restriction was the main perinatal outcome of preeclampsia.
摘要：
■COVID-19是一种感染性病理，在怀孕期间显示血管变化，以及胎盘。这项研究的主要目的是评估住院妊娠合并COVID-19的孕妇中先兆子痫的患病率和危险因素。以及比较患有COVID-19和先兆子痫的住院孕妇与无先兆子痫的孕妇的孕产妇和围产期结局。
■来自两家三级医院的100名住院孕妇的前瞻性队列研究，诊断为COVID-19，分为两组：PE组（患有COVID-19和子痫前期的孕妇）和PE组（患有COVID-19的孕妇）。这些孕妇有患病率，危险因素，孕产妇和围产期数据分析。
■先兆子痫的患病率为11%。重度COVID-19是子痫前期的主要危险因素(OR=8.18[CI1.53-43.52]),胎儿生长受限是围产期的主要结局(OR=8.90[CI1.52-38.4])。PE+组合并症更常见（63.6%vs31.5%，p=0.03),以及早产(81.8%和41.6%，p=0.02),低出生体重(63.6%vs24.7%，p=0.01),以及新生儿重症监护的需要(63.6%vs27.0%，p=0.03)。患有PE的孕妇在重症监护病房的住院时间是其两倍（RR=2.35[CI1.34-4.14]）。尽管妊娠合并PE的孕妇死亡更为频繁，没有统计学意义。
■住院妊娠合并COVID-19的先兆子痫患病率为11%。重度COVID-19是先兆子痫的主要危险因素，相关合并症增加了先兆子痫的风险。在重症监护病房长期住院是主要的母体结局，胎儿生长受限是子痫前期的主要围产期结局。
■来自两家三级医院的100名住院孕妇的前瞻性队列研究，诊断为COVID-19，分为两组：PE组（患有COVID-19和子痫前期的孕妇）和PE组（患有COVID-19的孕妇）。这些孕妇有患病率，危险因素，孕产妇和围产期数据分析。
■先兆子痫的患病率为11%。重度COVID-19是子痫前期的主要危险因素(OR=8.18[CI1.53-43.52]),胎儿生长受限是围产期的主要结局(OR=8.90[CI1.52-38.4])。PE+组合并症更常见（63.6%vs31.5%，p=0.03),以及早产(81.8%和41.6%，p=0.02),低出生体重(63.6%vs24.7%，p=0.01),以及新生儿重症监护的需要(63.6%vs27.0%，p=0.03)。患有PE的孕妇在重症监护病房的住院时间是其两倍（RR=2.35[CI1.34-4.14]）。尽管妊娠合并PE的孕妇死亡更为频繁，没有统计学意义。
■住院妊娠合并COVID-19的先兆子痫患病率为11%。重度COVID-19是先兆子痫的主要危险因素，相关合并症增加了先兆子痫的风险。在重症监护病房长期住院是主要的母体结局，胎儿生长受限是子痫前期的主要围产期结局。
