PDF(Pubmed)
Abstract：
UNASSIGNED: Little is known about the frequency and impact of the persistent headache and about the incidence of chronic daily headache (CDH) after coronavirus disease 2019 (COVID-19). The aim of this prospective cohort study was to assess the incidence, risk factors, characteristics, and impact of CDH in patients with COVID-19.
UNASSIGNED: In the first stage, 288 patients were interviewed by telephone after the acute phase of COVID-19. Subsequently, 199 patients who presented headache were reinterviewed at least one year after COVID-19. Headaches that persisted beyond the acute phase of COVID-19 for three or more months and presented frequency ≥ 45 days over the first three months were considered to be CDH.
UNASSIGNED: One hundred and twenty-three patients were included, 56% were females; median age: 50 years (25th and 75th percentile: 41;58). The headache persisted beyond the acute phase of COVID-19 in 52%, and 20.3% had CDH (95% confidence interval: 13.6-28.2). Individuals who previously had headaches and who had headaches of greater intensity during the acute phase were at higher risk of developing CDH. The group with CDH included more females, greater impact of headache, more persistence of headache beyond the 120th day of COVID-19 and less throbbing headache than did the other individuals whose headache persisted.
UNASSIGNED: Patients who had COVID-19 had a high incidence of CDH. Previous headache and greater intensity of headache were associated with higher risk of CDH.
UNASSIGNED: In the first stage, 288 patients were interviewed by telephone after the acute phase of COVID-19. Subsequently, 199 patients who presented headache were reinterviewed at least one year after COVID-19. Headaches that persisted beyond the acute phase of COVID-19 for three or more months and presented frequency ≥ 45 days over the first three months were considered to be CDH.
UNASSIGNED: One hundred and twenty-three patients were included, 56% were females; median age: 50 years (25th and 75th percentile: 41;58). The headache persisted beyond the acute phase of COVID-19 in 52%, and 20.3% had CDH (95% confidence interval: 13.6-28.2). Individuals who previously had headaches and who had headaches of greater intensity during the acute phase were at higher risk of developing CDH. The group with CDH included more females, greater impact of headache, more persistence of headache beyond the 120th day of COVID-19 and less throbbing headache than did the other individuals whose headache persisted.
UNASSIGNED: Patients who had COVID-19 had a high incidence of CDH. Previous headache and greater intensity of headache were associated with higher risk of CDH.
摘要：
■关于2019年冠状病毒病（COVID-19）后持续性头痛的频率和影响以及慢性每日头痛（CDH）的发生率知之甚少。这项前瞻性队列研究的目的是评估发病率，危险因素，特点,以及CDH对COVID-19患者的影响。
■在第一阶段，在COVID-19急性期后，对288例患者进行了电话采访。随后，199名出现头痛的患者在COVID-19后至少一年接受了重新采访。持续超过COVID-19急性期三个月或三个月以上且在前三个月内出现频率≥45天的头痛被认为是CDH。
■纳入了123名患者，56%为女性;中位年龄:50岁(第25和第75百分位数:41;58)。52％的人头痛持续超过COVID-19的急性期，20.3%患有CDH（95%置信区间：13.6-28.2）。以前有头痛和在急性期有更大强度头痛的个体发生CDH的风险更高。患有CDH的人群包括更多的女性，头痛的影响更大，与其他持续头痛的个体相比，在COVID-19的第120天之后，头痛的持续时间更多，而抽搐性头痛更少。
■患有COVID-19的患者CDH的发病率很高。以前的头痛和更大的头痛强度与更高的CDH风险相关。
■在第一阶段，在COVID-19急性期后，对288例患者进行了电话采访。随后，199名出现头痛的患者在COVID-19后至少一年接受了重新采访。持续超过COVID-19急性期三个月或三个月以上且在前三个月内出现频率≥45天的头痛被认为是CDH。
■纳入了123名患者，56%为女性;中位年龄:50岁(第25和第75百分位数:41;58)。52％的人头痛持续超过COVID-19的急性期，20.3%患有CDH（95%置信区间：13.6-28.2）。以前有头痛和在急性期有更大强度头痛的个体发生CDH的风险更高。患有CDH的人群包括更多的女性，头痛的影响更大，与其他持续头痛的个体相比，在COVID-19的第120天之后，头痛的持续时间更多，而抽搐性头痛更少。
■患有COVID-19的患者CDH的发病率很高。以前的头痛和更大的头痛强度与更高的CDH风险相关。
