Mesh : Snake Bites / complications Humans Female Antivenins / therapeutic use Animals Adult Skin Transplantation / methods Debridement / methods Necrosis / etiology

来  源:   DOI:10.59556/japi.72.0560

Abstract:
Many snakebite deaths in India may remain unreported as these patients still seek treatment from traditional healers or quacks. Though local and systemic toxicity due to snake envenomation is quite common, the clinical presentation as disseminated extensive tissue damage and ulceration is not seen. We present a lady who presented with extensive skin erosions with tissue necrosis in all four limbs and the trunk. The case was successfully managed with antisnake venom, wound debridement, and split skin grafting. Early antisnake venom halts the progression of tissue damage effects of snake venom. The future treatment of these extensive ulcerations may be the use of drugs that can inhibit the hydrolyzing enzymes of snake venom. The case also stresses the need for excellent wound care after the management of systemic envenomation with antivenom treatment.
摘要:
印度的许多蛇咬伤死亡可能仍未报告,因为这些患者仍在寻求传统治疗师或庸医的治疗。尽管由于蛇毒引起的局部和全身毒性很常见,临床表现为播散性广泛组织损伤和溃疡未见。我们介绍了一位女士,她的四肢和躯干都出现了广泛的皮肤糜烂,组织坏死。这个病例用抗蛇毒成功处理,伤口清创术,和裂口植皮。早期的反蛇毒会阻止蛇毒组织损伤作用的发展。这些广泛的溃疡的未来治疗可能是使用可以抑制蛇毒水解酶的药物。该案例还强调,在使用抗蛇毒血清治疗进行全身毒液处理后,需要出色的伤口护理。
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