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Abstract：
BACKGROUND: IgG4-related diseases are very uncommon, and its diagnosis and treatment are complicated as it encompasses multiple disciplines.
METHODS: A 77-year-old woman was admitted with a jaw mass and nausea and vomiting. Laboratory tests showed elevated serum IgG4, pituitary MRI suggested thickening of the pituitary stalk, and head and neck CT suggested orbital and mandibular masses. Patients with mandibular mass were diagnosed with Mikulicz\'s disease with IgG4-related hypophysitis. We found no other evidence of causing thickening of the pituitary stalk. She was given oral prednisolone 30 mg daily, and her nausea and vomiting improved significantly, and the mandibular and ocular masses decreased in size.
CONCLUSIONS: Mikulicz\'s disease combined with IgG4-related hypophysitis is a rare case of IgG4-RD in elderly women. IgG4-RD is one of the causes of head and neck exocrine gland mass and pituitary stalk thickening in the elderly.
METHODS: A 77-year-old woman was admitted with a jaw mass and nausea and vomiting. Laboratory tests showed elevated serum IgG4, pituitary MRI suggested thickening of the pituitary stalk, and head and neck CT suggested orbital and mandibular masses. Patients with mandibular mass were diagnosed with Mikulicz\'s disease with IgG4-related hypophysitis. We found no other evidence of causing thickening of the pituitary stalk. She was given oral prednisolone 30 mg daily, and her nausea and vomiting improved significantly, and the mandibular and ocular masses decreased in size.
CONCLUSIONS: Mikulicz\'s disease combined with IgG4-related hypophysitis is a rare case of IgG4-RD in elderly women. IgG4-RD is one of the causes of head and neck exocrine gland mass and pituitary stalk thickening in the elderly.
摘要：
背景：IgG4相关疾病非常罕见，它的诊断和治疗是复杂的，因为它涵盖了多个学科。
方法：一名77岁女性因颌骨肿块和恶心呕吐入院。实验室检查显示血清IgG4升高，垂体MRI提示垂体柄增厚，头颈部CT提示眶及下颌肿块。下颌肿块患者被诊断为Mikulicz病合并IgG4相关垂体炎。我们没有发现其他导致垂体柄增厚的证据。她每天口服强的松龙30毫克，她的恶心和呕吐明显改善，下颌和眼部肿块的大小减少。
结论：Mikulicz病合并IgG4相关性垂体炎是老年女性罕见的IgG4-RD病例。IgG4-RD是老年人头颈部外分泌腺肿块和垂体柄增厚的原因之一。
方法：一名77岁女性因颌骨肿块和恶心呕吐入院。实验室检查显示血清IgG4升高，垂体MRI提示垂体柄增厚，头颈部CT提示眶及下颌肿块。下颌肿块患者被诊断为Mikulicz病合并IgG4相关垂体炎。我们没有发现其他导致垂体柄增厚的证据。她每天口服强的松龙30毫克，她的恶心和呕吐明显改善，下颌和眼部肿块的大小减少。
结论：Mikulicz病合并IgG4相关性垂体炎是老年女性罕见的IgG4-RD病例。IgG4-RD是老年人头颈部外分泌腺肿块和垂体柄增厚的原因之一。
