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Abstract：
For successful root canal treatment, adequate chemomechanical instrumentation to eliminate microorganisms and pulp tissue is crucial. This study aims to assess the organic tissue dissolving activity of various irrigation solutions on bovine tooth pulp tissue. 40 extracted bovine mandibular anterior teeth (n = 10) were used for the study. Bovine pulp pieces (25 ± 5 mg) were placed in 1.5 ml Eppendorf tubes. Each tooth pulp sample was then covered with 1.5 ml of different irrigation solutions, dividing them into four groups: Group 1 with freshly prepared 5% Boric acid, Group 2 with 5% NaOCl, Group 3 with Irritrol, and Group 4 with Saline. Samples were left at room temperature for 30 min, then dried and reweighed. The efficacy of tissue dissolution ranked from highest to lowest was found to be NaOCl, Boric Acid, Irritrol, and saline (p < 0.05). It was observed that the decrease in the NaOCl group was greater than the decrease in the Irritrol and saline groups, and the decrease in the Boric acid group was significantly greater than the decrease in the saline group (p < 0.05). It also emphasizes the need for future studies to further investigate the effects of Irritrol and Boric Acid on tissue dissolution.
摘要：
对于成功的根管治疗，足够的化学机械仪器来消除微生物和牙髓组织是至关重要的。这项研究旨在评估各种冲洗溶液对牛牙髓组织的有机组织溶解活性。将40颗提取的牛下颌前牙(n=10)用于研究。将牛浆块(25±5mg)置于1.5mlEppendorf管中。然后用1.5ml不同的冲洗溶液覆盖每个牙髓样品，将它们分为四组：第1组，新鲜制备的5％硼酸，含5%NaOCl的第2组,第三组用Irritrol,和第4组盐水。样品在室温下放置30分钟，然后干燥并重新称重。发现从最高到最低的组织溶解功效是NaOCl，硼酸,Irritrol,和生理盐水（p<0.05）。观察到NaOCl组的减少大于Irritrol和盐水组的减少，硼酸组的下降幅度明显大于生理盐水组的下降幅度(p<0.05)。它还强调需要进一步研究Irritrol和硼酸对组织溶解的影响。
