m5C 甲基化的 lncRncr3 - MeCP2 相互作用限制 miR124a 引发的神经发生。
Mesh : MicroRNAs / metabolism genetics Methyl-CpG-Binding Protein 2 / metabolism genetics Neurogenesis / genetics Animals Mice RNA, Long Noncoding / metabolism genetics Neural Stem Cells / metabolism cytology Brain / metabolism embryology Humans Cell Differentiation DNA Methylation Polypyrimidine Tract-Binding Protein / metabolism genetics Cell Proliferation Mice, Inbred C57BL 5-Methylcytosine / metabolism analogs & derivatives Male Exons / genetics Neurons / metabolism Ribonuclease III
来 源:
DOI:10.1038/s41467-024-49368-w
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