PDF(Pubmed)
Abstract：
BACKGROUND: The purpose of this study was to clarify (1) the differences in cortical bone thickness (CBT) of the tibial diaphysis between healthy and osteoarthritic knees and (2) the influences of the femorotibial angle (FTA) and inclination of the medial compartment of the proximal tibia (MCT) on tibial CBT.
METHODS: The study assessed 60 subjects with varus knee osteoarthritis (OA) (22 males and 38 females; mean age, 74 ± 7 years) and 53 healthy elderly subjects (28 males and 25 females; mean age, 70 ± 6 years). Three-dimensional estimated CBT of the tibial diaphysis was automatically calculated for 2752-11,296 points using high-resolution measurements from CT. The standardized CBT was assessed in 24 regions by combining six heights and four areas. Additionally, the association between the CBT, each FTA, and MCT inclination was investigated.
RESULTS: The OA group showed a thicker CBT in the medial areas than in the lateral areas of the proximal tibia, while the healthy group had a thicker lateral CBT. The medial-to-lateral ratio of the proximal tibia was significantly higher in the OA group than in the healthy group. The proximal-medial CBT correlated with FTA and MCT inclinations in the OA group.
CONCLUSIONS: This study demonstrated that varus osteoarthritic knees showed a different trend of proximal-medial CBT with associations in FTA and MCT inclination from healthy knees, possibly due to medial load concentration.
METHODS: The study assessed 60 subjects with varus knee osteoarthritis (OA) (22 males and 38 females; mean age, 74 ± 7 years) and 53 healthy elderly subjects (28 males and 25 females; mean age, 70 ± 6 years). Three-dimensional estimated CBT of the tibial diaphysis was automatically calculated for 2752-11,296 points using high-resolution measurements from CT. The standardized CBT was assessed in 24 regions by combining six heights and four areas. Additionally, the association between the CBT, each FTA, and MCT inclination was investigated.
RESULTS: The OA group showed a thicker CBT in the medial areas than in the lateral areas of the proximal tibia, while the healthy group had a thicker lateral CBT. The medial-to-lateral ratio of the proximal tibia was significantly higher in the OA group than in the healthy group. The proximal-medial CBT correlated with FTA and MCT inclinations in the OA group.
CONCLUSIONS: This study demonstrated that varus osteoarthritic knees showed a different trend of proximal-medial CBT with associations in FTA and MCT inclination from healthy knees, possibly due to medial load concentration.
摘要：
背景：这项研究的目的是阐明（1）健康膝关节和骨关节炎膝关节之间胫骨骨干皮质骨厚度（CBT）的差异，以及（2）股骨角度（FTA）和胫骨近端内侧室（MCT）的倾斜度对胫骨CBT的影响。
方法：该研究评估了60名患有内翻膝骨关节炎（OA）的受试者（男性22名，女性38名；平均年龄，74±7岁）和53名健康的老年受试者（男性28名，女性25名；平均年龄，70±6年）。使用CT的高分辨率测量结果，自动计算了2752-11,296点的胫骨骨干的三维估计CBT。通过结合六个高度和四个区域，在24个地区评估了标准化的CBT。此外,CBT之间的联系，每个FTA，并对MCT倾向进行了调查。
结果：OA组显示胫骨近端内侧区域的CBT比外侧区域厚，而健康组侧方CBT较厚。OA组胫骨近端内侧外侧比值明显高于健康组。OA组的近内侧CBT与FTA和MCT倾斜相关。
结论：这项研究表明，内翻骨关节炎膝关节表现出与健康膝关节不同的近端内侧CBT趋势，与FTA和MCT倾斜有关，可能是由于中间负荷集中。
方法：该研究评估了60名患有内翻膝骨关节炎（OA）的受试者（男性22名，女性38名；平均年龄，74±7岁）和53名健康的老年受试者（男性28名，女性25名；平均年龄，70±6年）。使用CT的高分辨率测量结果，自动计算了2752-11,296点的胫骨骨干的三维估计CBT。通过结合六个高度和四个区域，在24个地区评估了标准化的CBT。此外,CBT之间的联系，每个FTA，并对MCT倾向进行了调查。
结果：OA组显示胫骨近端内侧区域的CBT比外侧区域厚，而健康组侧方CBT较厚。OA组胫骨近端内侧外侧比值明显高于健康组。OA组的近内侧CBT与FTA和MCT倾斜相关。
结论：这项研究表明，内翻骨关节炎膝关节表现出与健康膝关节不同的近端内侧CBT趋势，与FTA和MCT倾斜有关，可能是由于中间负荷集中。
