关键词: Culture-independent MLST Haemophilus influenzae Multi-locus sequence typing cross-infection non-cystic fibrosis bronchiectasis

来  源:   DOI:10.1016/j.diagmicrobio.2024.116327

Abstract:
Whether cross-infection of respiratory pathogens between patients with non-cystic fibrosis bronchiectasis occurs is debated. Investigation with traditional microbiological culture risks simplifying the lung microbiome. We demonstrate the use of culture-independent Multilocus sequence typing to screen for Haemophilus influenzae strain types in a cohort of twenty-eight patients with non-cystic fibrosis bronchiectasis.
摘要:
非囊性纤维化支气管扩张患者之间是否会发生呼吸道病原体的交叉感染存在争议。传统微生物培养的研究存在简化肺部微生物组的风险。我们证明了在28例非囊性纤维化支气管扩张患者的队列中,使用不依赖培养的多位点序列分型来筛选流感嗜血杆菌菌株类型。
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