Abstract：
Calcinosis cutis is a condition that is commonly associated with autoimmune connective tissue diseases. It is characterized by the deposition of insoluble calcium salts in the skin and subcutaneous tissue, which can cause pain, impair function, and have significant impacts on quality of life. Calcinosis cutis is difficult to manage because there is no generally accepted treatment: evidence supporting treatments is mostly comprised of case reports and case series, sometimes yielding mixed findings. Both pharmacologic and procedural interventions have been proposed to improve calcinosis cutis, and each may be suited to different clinical scenarios. This review summarizes current treatment options for calcinosis cutis, with discussion of recommendations based on patient-specific factors and disease severity.
摘要：
角质层钙化症是一种通常与自身免疫性结缔组织疾病相关的疾病。它的特点是不溶性钙盐沉积在皮肤和皮下组织中，会引起疼痛，损害功能，并对生活质量产生重大影响。由于没有普遍接受的治疗方法，皮肤钙化症难以治疗：支持治疗的证据主要包括病例报告和病例系列，有时会产生混合的发现。已经提出了药物和程序干预措施来改善钙质角质症，并且每个可以适合于不同的临床场景。这篇综述总结了目前骨灰质沉着的治疗选择，讨论基于患者特异性因素和疾病严重程度的建议。
