Abstract：
BACKGROUND: Of the neurodegenerative diseases, Parkinson\'s disease is recognised to have the fastest growing prevalence. It is unclear whether this is due to the ageing global population alone, with several environmental factors increasingly implicated in changing prevalence rates. Large data sets have been used nationally and globally to help predict future disease burden. However, the reliability of such sources is yet unknown for Parkinson\'s disease.
CONCLUSIONS: This review discusses the methods used in all published UK prevalence studies conducted to date. Direct comparison between prevalence figures obtained from the 10 to discussed prevalence studies is precluded due to differences in methodology for case ascertainment and diagnosis. Age adjusted estimates vary from 105/100,000 to 168/100,000.
CONCLUSIONS: These studies demonstrate no overall trend in changing prevalence figures between 1961 and 2007. No difference in prevalence trends were seen for those living in rural or urban areas. Differences between ethnic groups, for example, remains an under explored area.
CONCLUSIONS: This review discusses the methods used in all published UK prevalence studies conducted to date. Direct comparison between prevalence figures obtained from the 10 to discussed prevalence studies is precluded due to differences in methodology for case ascertainment and diagnosis. Age adjusted estimates vary from 105/100,000 to 168/100,000.
CONCLUSIONS: These studies demonstrate no overall trend in changing prevalence figures between 1961 and 2007. No difference in prevalence trends were seen for those living in rural or urban areas. Differences between ethnic groups, for example, remains an under explored area.
摘要：
背景：在神经退行性疾病中，帕金森病被认为是发病率增长最快的疾病。目前尚不清楚这是否仅仅是由于全球人口老龄化造成的。随着几个环境因素越来越多地影响患病率的变化。大型数据集已在全国和全球范围内用于帮助预测未来的疾病负担。然而,这些来源的可靠性对于帕金森氏病还不清楚。
结论：本综述讨论了迄今为止所有已发表的英国患病率研究中使用的方法。由于病例确定和诊断方法的差异，无法直接比较从10项讨论的患病率研究中获得的患病率数字。年龄调整后的估计数从105/100,000到168/100,000不等。
结论：这些研究表明，在1961年至2007年间，患病率数字没有总体变化趋势。对于生活在农村或城市地区的人群，患病率趋势没有差异。种族之间的差异，例如,仍然是一个探索不足的地区。
结论：本综述讨论了迄今为止所有已发表的英国患病率研究中使用的方法。由于病例确定和诊断方法的差异，无法直接比较从10项讨论的患病率研究中获得的患病率数字。年龄调整后的估计数从105/100,000到168/100,000不等。
结论：这些研究表明，在1961年至2007年间，患病率数字没有总体变化趋势。对于生活在农村或城市地区的人群，患病率趋势没有差异。种族之间的差异，例如,仍然是一个探索不足的地区。
