Abstract：
In 2019, an estimated 4.95 million deaths were linked to antimicrobial resistance (AMR). Vaccines can prevent many of these deaths by averting both drug-sensitive and resistant infections, reducing antibiotic usage, and lowering the likelihood of developing resistance genes. However, their role in mitigating AMR is currently underutilized. This article builds upon previous research that utilizes Vaccine Value Profiles-tools that assess the health, socioeconomic, and societal impact of pathogens-to inform vaccine development. We analyze the effects of 16 pathogens, covered by Vaccine Value Profiles, on AMR, and explore how vaccines could reduce AMR. The article also provides insights into vaccine development and usage. Vaccines are crucial in lessening the impact of infectious diseases and curbing the development of AMR. To fully realize their potential, vaccines must be more prominently featured in the overall strategy to combat AMR. This requires ongoing investment in research and development of new vaccines and the implementation of additional prevention and control measures to address this global threat effectively.
摘要：
2019年，估计有495万人死亡与抗菌素耐药性（AMR）有关。疫苗可以通过避免药物敏感性和耐药性感染来预防许多此类死亡。减少抗生素的使用，并降低产生抗性基因的可能性。然而,它们在减轻AMR方面的作用目前未得到充分利用。本文基于先前的研究，利用疫苗价值概况-评估健康状况的工具，社会经济,以及病原体的社会影响-为疫苗开发提供信息。我们分析了16种病原体的影响，疫苗价值概况涵盖，在AMR上，并探索疫苗如何降低AMR。本文还提供了有关疫苗开发和使用的见解。疫苗对于减轻传染病的影响和遏制AMR的发展至关重要。为了充分发挥他们的潜力，疫苗必须在对抗AMR的总体战略中更加突出。这需要持续投资于新疫苗的研究和开发，并实施更多的预防和控制措施，以有效应对这一全球威胁。
