Mesh : Humans Female Platelet-Rich Plasma Prospective Studies Adult Endometrium Infertility, Female / therapy blood Anti-Mullerian Hormone / blood Pregnancy Ovarian Reserve Treatment Outcome

来  源:   DOI:10.1097/MD.0000000000038554   PDF(Pubmed)

Abstract:
A prospective cohort study investigated the effectiveness of platelet-rich plasma (PRP) infusion for refractory thin endometrium in 38 infertile patients. Patients showed significant improvement in endometrial thickness post-PRP injection, leading to successful implantation and pregnancy. The study revealed a negative correlation between antimullerian hormone (AMH) levels and the need for PRP interventions, suggesting higher ovarian reserve may reduce the necessity for repeated treatments. This implies AMH levels could serve as a prognostic indicator for treatment outcomes, aiding clinicians in optimizing protocols and reducing patient burden. Further research is needed to confirm these findings in larger and more diverse populations, along with exploring long-term reproductive success rates post-PRP treatment.
摘要:
一项前瞻性队列研究调查了38例不育患者输注富血小板血浆(PRP)对难治性薄型子宫内膜的有效性。PRP注射后子宫内膜厚度显著改善,导致成功的植入和怀孕。该研究揭示了抗苗勒管激素(AMH)水平与PRP干预的需求之间的负相关,提示较高的卵巢储备可能降低重复治疗的必要性.这意味着AMH水平可以作为治疗结果的预后指标,帮助临床医生优化方案并减轻患者负担。需要进一步的研究来证实这些发现在更大和更多样化的人群中,同时探索PRP治疗后的长期生殖成功率。
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