PDF(Pubmed)
Abstract：
Mantle cell lymphoma (MCL) can, in a few reported cases, create an exaggerated mosquito bite response, leading to numerous bullae and significant edema. The phenomenon is further complicated by the observance of a concurrent Epstein-Barr virus (EBV) reactivation. The current literature provides general information on treatment that most practitioners would consider when attempting to treat an arthropod hypersensitivity reaction, such as topical or systemic corticosteroids. However, no information has been published to date that details a preventive and steroid-sparing approach to treating this phenomenon, without simultaneously treating the MCL. MCL can be indolent in nature and does not always require prompt treatment. The purpose of this case report is to discuss the successful treatment of a rare disorder with a steroid-sparing regimen. The steroid-sparing regimen used consisted of oral doxycycline 100mg twice daily, cetirizine 20mg once daily, and valacyclovir 1g daily, which resulted in sustained reduction in bullous eruptions.
摘要：
套细胞淋巴瘤（MCL）可以，在一些报道的案例中，创造一个夸张的蚊虫叮咬反应，导致大量大疱和明显的水肿。由于观察到同时发生的爱泼斯坦-巴尔病毒（EBV）的再激活，这种现象变得更加复杂。目前的文献提供了大多数医生在尝试治疗节肢动物过敏反应时会考虑的一般治疗信息，如局部或全身皮质类固醇。然而,迄今为止，还没有公布任何信息，详细说明一种预防性和节省类固醇的方法来治疗这种现象，不同时治疗MCL。MCL本质上可以是惰性的，并不总是需要及时治疗。此病例报告的目的是讨论使用类固醇保留方案成功治疗罕见疾病。使用的类固醇保留方案包括口服强力霉素100mg，每天两次，西替利嗪20mg，每日一次，伐昔洛韦每天1g，这导致了大疱性喷发的持续减少。
