RESULTS: Among the six polyol compounds tested, PG was most toxic and lethal followed by glycerol and erythritol (P < 0.001) compared to the control (sucrose). PG induced acute mortality at different tested concentrations. In the erythritol- and glycerol-fed groups, a dose-dependent effect on mortality was observed. Glycerol evidently reduced fecundity and egg-hatchability in gonotrophic cycles G1 and G2. Sucrose was the preferred food source (48%), followed by erythritol (18%), PG (10%) and glycerol (8%). Ingestion of polyols increased peroxide levels in mosquito guts, which persisted for extended durations ultimately resulting in rapid mortality (P < 0.05).
CONCLUSIONS: The present study highlights the usefulness of sugar polyols for the development of toxic sugar baits with minimal yet effective ingredients. Further research could be focused on field experiments and on the exploration of synergistic effects of different polyols for optimization of field applications. © 2024 Society of Chemical Industry.
结果:在测试的六种多元醇化合物中,与对照(蔗糖)相比,PG的毒性和致死性最强,其次是甘油和赤藓糖醇(P<0.001)。PG在不同测试浓度下诱导急性死亡。在红霉素和甘油喂养组中,观察到对死亡率的剂量依赖性效应.甘油显着降低了促性腺激素周期G1和G2的繁殖力和卵孵化率。蔗糖是首选食物来源(48%),其次是赤藓糖醇(18%),PG(10%)和甘油(8%)。摄入多元醇会增加蚊子肠道中的过氧化物水平,持续时间延长,最终导致快速死亡率(P<0.05)。
结论:本研究强调了糖多元醇在开发具有最少有效成分的有毒糖诱饵方面的有用性。进一步的研究可以集中在现场实验和探索不同多元醇的协同作用,以优化现场应用。©2024化学工业学会。