METHODS: This single-center retrospective study used propensity-matched scoring based on the patients\' baseline characteristics (age, sex, indication, bowel preparation, endoscopist, colonoscope type, and withdrawal time) to compare the results of patients who underwent chromoendoscopy using WLI or TXI at the Toyoshima Endoscopy Clinic. The differences in polyp detection rates and the mean number of detected polyps per colonoscopy were determined between the TXI and WLI groups.
RESULTS: After propensity score matching, 1970 patients were enrolled into each imaging modality group. The mean patient age was 57.2 ± 12.5 years, and 44.5% of the cohort were men. The ADR was higher in the TXI group than in the WLI group (55.0% vs 49.4%, odds ratio: 1.25). High-risk ADR were more common in the TXI group than in the WLI group (17.6% vs 12.8%; OR: 1.45). The mean number of adenomas per colonoscopy (APC) was higher in the TXI group than in the WLI group (1.187 vs 0.943, OR: 1.12). APC with a flat morphology (1.093 vs 0.848, OR: 1.14) and APC of <6 mm (0.992 vs 0.757, OR: 1.16) were higher in the TXI group than in the WLI group.
CONCLUSIONS: Compared to WLI, TXI improved the ADR in patients who underwent chromoendoscopy based on actual clinical data.
方法:此单中心回顾性研究使用基于患者基线特征的倾向匹配评分(年龄,性别,指示,肠道准备,内窥镜医师,结肠镜类型,和停药时间),以比较在丰岛内窥镜检查诊所使用WLI或TXI进行色素内窥镜检查的患者的结果。确定TXI组和WLI组之间的息肉检出率和每次结肠镜检查检测到的息肉平均数量的差异。
结果:在倾向得分匹配后,1970例患者被纳入每个成像模式组。患者平均年龄为57.2±12.5岁,其中44.5%为男性.TXI组的ADR高于WLI组(55.0%vs49.4%,赔率比:1.25)。TXI组比WLI组更常见高危ADR(17.6%vs12.8%;OR:1.45)。TXI组每次结肠镜检查(APC)的平均腺瘤数量高于WLI组(1.187vs0.943,OR:1.12)。与WLI组相比,TXI组形态平坦的APC(1.093vs0.848,OR:1.14)和<6mm的APC(0.992vs0.757,OR:1.16)较高。
结论:与WLI相比,根据实际临床数据,TXI改善了行色素内镜检查的患者的ADR。