关键词: COVID-19 SARS-CoV-2 dexmedetomidine fever

Mesh : Humans Dexmedetomidine / adverse effects COVID-19 / complications Fever / chemically induced SARS-CoV-2 Hypnotics and Sedatives / adverse effects Male Pandemics Pneumonia, Viral / drug therapy complications Coronavirus Infections / drug therapy complications Betacoronavirus Middle Aged Adrenergic alpha-2 Receptor Agonists / adverse effects Drug Fever

来  源:   DOI:10.1177/23247096241260959   PDF(Pubmed)

Abstract:
Patients infected with COVID-19 can develop coinfections or acute respiratory disorder that result in ventilation. Dexmedetomidine is a common medication used to sedate ventilated patients in the intensive care unit and for nonintubated patients prior to a surgical procedure. As a highly selective alpha-2 agonist, dexmedetomidine provides sedation while reducing the need for anxiolytics or opioids. However, previous case reports suggest dexmedetomidine can induce fever in a variety of conditions. The purpose of this case report is to describe a patient who acquired a fever of 42.6°C in the setting of COVID-19 after administration of dexmedetomidine.
摘要:
感染COVID-19的患者可发生合并感染或急性呼吸系统疾病,导致通气。右美托咪定是一种常见的药物,用于在重症监护病房中镇静通气的患者以及在外科手术之前用于非插管的患者。作为高选择性α-2激动剂,右美托咪定提供镇静作用,同时减少抗焦虑药或阿片类药物的需要.然而,以前的病例报告显示右美托咪定可在多种情况下引起发热.本病例报告的目的是描述一名患者在服用右美托咪定后在COVID-19环境中发烧42.6°C。
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