Abstract：
BACKGROUND: IgG4-related disease (IgG4-RD) is an immune-mediated systemic inflammatory fibrotic disease, which is a relatively rare and novel disease that can involve multiple organs or tissues, with variable clinical manifestations, and for which pulmonary involvement has been reported relatively infrequently.
METHODS: Here we report a case of pulmonary infection that was initially suspected and received anti-inflammatory treatment, but the symptoms did not improve. CT examination indicated progression of the pulmonary lesion, and the nature of the lesion could not be determined by tracheoscopy and bronchoalveolar lavage. The diagnosis of IgG4 related lung disease (IgG4-RLD) was confirmed by percutaneous lung biopsy. A joint literature analysis was conducted to improve clinicians\' understanding of this disease.
RESULTS: The patient\'s history, symptoms, signs and relevant examination results were analyzed. The final diagnosis was IgG4-RLD.
CONCLUSIONS: When the clinical symptoms and imaging manifestations of the patients are consistent with IgG4-RLD, pathological examination can be appropriately performed to clarify the nature of the lesions. More consideration should be given to the possibility of disease diagnosis to avoid misdiagnosis and underdiagnosis, and proper treatment should be given at an early stage.
METHODS: Here we report a case of pulmonary infection that was initially suspected and received anti-inflammatory treatment, but the symptoms did not improve. CT examination indicated progression of the pulmonary lesion, and the nature of the lesion could not be determined by tracheoscopy and bronchoalveolar lavage. The diagnosis of IgG4 related lung disease (IgG4-RLD) was confirmed by percutaneous lung biopsy. A joint literature analysis was conducted to improve clinicians\' understanding of this disease.
RESULTS: The patient\'s history, symptoms, signs and relevant examination results were analyzed. The final diagnosis was IgG4-RLD.
CONCLUSIONS: When the clinical symptoms and imaging manifestations of the patients are consistent with IgG4-RLD, pathological examination can be appropriately performed to clarify the nature of the lesions. More consideration should be given to the possibility of disease diagnosis to avoid misdiagnosis and underdiagnosis, and proper treatment should be given at an early stage.
摘要：
背景：IgG4相关疾病（IgG4-RD）是一种免疫介导的全身性炎症性纤维化疾病，这是一种相对罕见和新颖的疾病，可能涉及多个器官或组织，临床表现多变，而肺部受累的报道相对较少。
方法：在这里，我们报告一例最初怀疑并接受抗炎治疗的肺部感染，但症状没有改善。CT检查提示肺部病变进展,并且无法通过气管镜检查和支气管肺泡灌洗确定病变的性质。通过经皮肺活检证实了IgG4相关性肺疾病(IgG4-RLD)的诊断。进行了联合文献分析，以提高临床医生对这种疾病的认识。
结果：患者病史，症状,对体征和相关检查结果进行分析。最终诊断为IgG4-RLD。
结论：当患者的临床症状和影像学表现与IgG4-RLD一致时，可以适当进行病理检查以澄清病变的性质。应更多考虑疾病诊断的可能性,避免误诊,漏诊,应该在早期给予适当的治疗。
方法：在这里，我们报告一例最初怀疑并接受抗炎治疗的肺部感染，但症状没有改善。CT检查提示肺部病变进展,并且无法通过气管镜检查和支气管肺泡灌洗确定病变的性质。通过经皮肺活检证实了IgG4相关性肺疾病(IgG4-RLD)的诊断。进行了联合文献分析，以提高临床医生对这种疾病的认识。
结果：患者病史，症状,对体征和相关检查结果进行分析。最终诊断为IgG4-RLD。
结论：当患者的临床症状和影像学表现与IgG4-RLD一致时，可以适当进行病理检查以澄清病变的性质。应更多考虑疾病诊断的可能性,避免误诊,漏诊,应该在早期给予适当的治疗。
