关键词: Dopaminergic drugs Parkinson’s disease dyskinesia motor symptoms non-motor symptoms tremor

来  源:   DOI:10.29399/npa.28634   PDF(Pubmed)

Abstract:
As a neurologist who has followed up countless Parkinson\'s patients over the last 32 years of my fifty-year career; I denied diagnosing myself with Parkinson\'s disease (PD), although the seldom mild involuntary \"twitches\" that occurred in the thumb of my right hand over a two-year period, resembled Parkinson\'s disease tremor. However, when these involuntary contractions became persistent; considering its similarity to characteristic resting tremor in typical PD, the positive effect of dopaminergic medications, the development of levodopa-induced dyskinesias and other non-motor symptoms, it was clear that the PD diagnosis was accurate. This situation naturally caused me anxiety, and for a year and a half, I kept my diagnosis hidden from everyone except a few close relatives. However, with the encouragement of a psychiatrist friend, when I was able to share my condition with my loved ones, I felt a relative reduction in the burden I was carrying and consequently experienced emotional relief. I am still able to carry out my daily activities independently with a rather low dose of medication, and my PD symptoms do not attract noticeable attention.
摘要:
作为一名神经科医生,在我50年职业生涯的最后32年里,他跟踪了无数帕金森病患者;我否认诊断自己患有帕金森病(PD),尽管在两年的时间里,我的右手拇指很少出现轻微的非自愿“抽搐”,类似于帕金森病的震颤。然而,当这些非自愿性收缩变得持续时;考虑到其与典型PD中特征性静息性震颤的相似性,多巴胺能药物的积极作用,左旋多巴引起的运动障碍和其他非运动症状的发展,很明显PD诊断是准确的.这种情况自然引起了我的焦虑,在一年半的时间里,除了几个近亲,我对所有人都隐瞒了我的诊断。然而,在一位精神病医生朋友的鼓励下,当我能够和我爱的人分享我的病情时,我感到自己背负的负担相对减轻,因此感到情感上的解脱。我仍然能够用相当低剂量的药物独立进行我的日常活动,我的PD症状没有引起注意。
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