PDF(Pubmed)
Abstract：
UNASSIGNED: Electroconvulsive therapy (ECT) is one of the biological therapies that is well tolerated and has a low risk of complications. Acute cardiovascular complications related to ECT such as ventricular arrhythmia, myocardial infarction and cardiac arrest have been recorded. Increased frontal QRS-T (fQRS-T) angle was associated with ventricular arrhythmia, sudden cardiac death and total mortality. In this study, we aimed to evaluate the effect of ECT on the myocardium using electrocardiography (ECG) parameters such as fQRS-T angle, QRS duration, QT and QTc interval.
UNASSIGNED: A total of 108 patients diagnosed with bipolar disorder (n=36), depressive disorder (n=70) and schizophrenia (n=2) who underwent ECT were included in this study. 12-lead surface ECG of all patients were taken before the ECT, 15 min. after ECT and 24 hour after ECT.
UNASSIGNED: QRS duration, QT interval and corrected QT (QTc) interval were not changed significantly during the follow-up period. However, we found that, fQRS-T angle was significantly increased 15 minutes after ECT compared to baseline angle (p<0.001). We also detected that this increase in fQRS-T angle 15 minutes after ECT was significantly reduced 24 hours after ECT (p=0.031). Meanwhile, there was no significant difference between baseline and 24th hour fQRS-T angle (p=0.154).
UNASSIGNED: In our study, a significant increase in fQRS-T angle was observed 15 min after ECT. However, the fQRS-T angle was found to return to normal after 24 hours. Our findings may indicate that ECT does not have a permanent side effect on the risk of cardiovascular events according to the fQRS-T angle.
UNASSIGNED: A total of 108 patients diagnosed with bipolar disorder (n=36), depressive disorder (n=70) and schizophrenia (n=2) who underwent ECT were included in this study. 12-lead surface ECG of all patients were taken before the ECT, 15 min. after ECT and 24 hour after ECT.
UNASSIGNED: QRS duration, QT interval and corrected QT (QTc) interval were not changed significantly during the follow-up period. However, we found that, fQRS-T angle was significantly increased 15 minutes after ECT compared to baseline angle (p<0.001). We also detected that this increase in fQRS-T angle 15 minutes after ECT was significantly reduced 24 hours after ECT (p=0.031). Meanwhile, there was no significant difference between baseline and 24th hour fQRS-T angle (p=0.154).
UNASSIGNED: In our study, a significant increase in fQRS-T angle was observed 15 min after ECT. However, the fQRS-T angle was found to return to normal after 24 hours. Our findings may indicate that ECT does not have a permanent side effect on the risk of cardiovascular events according to the fQRS-T angle.
摘要：
■电惊厥疗法（ECT）是耐受性良好且并发症风险低的生物疗法之一。与ECT相关的急性心血管并发症，如室性心律失常，心肌梗死和心脏骤停已被记录.额叶QRS-T（fQRS-T）角增加与室性心律失常有关，心源性猝死和总死亡率。在这项研究中,我们的目的是使用心电图（ECG）参数，如fQRS-T角评估ECT对心肌的影响，QRS持续时间,QT和QTc间期。
■共108名诊断为双相情感障碍的患者（n=36），本研究包括接受ECT治疗的抑郁症(n=70)和精神分裂症(n=2).所有患者在ECT前进行12导联体表心电图,15分钟ECT后和ECT后24小时。
■QRS持续时间，随访期间QT间期和校正QT(QTc)间期无明显变化。然而,我们发现,与基线角度相比,ECT后15分钟fQRS-T角度显著增加(p<0.001)。我们还检测到，ECT后15分钟fQRS-T角的增加在ECT后24小时显着降低（p=0.031）。同时,基线和24小时fQRS-T角之间没有显着差异（p=0.154）。
■在我们的研究中，ECT后15分钟观察到fQRS-T角显着增加。然而,24小时后fQRS-T角恢复正常.我们的发现可能表明，根据fQRS-T角度，ECT对心血管事件的风险没有永久性副作用。
■共108名诊断为双相情感障碍的患者（n=36），本研究包括接受ECT治疗的抑郁症(n=70)和精神分裂症(n=2).所有患者在ECT前进行12导联体表心电图,15分钟ECT后和ECT后24小时。
■QRS持续时间，随访期间QT间期和校正QT(QTc)间期无明显变化。然而,我们发现,与基线角度相比,ECT后15分钟fQRS-T角度显著增加(p<0.001)。我们还检测到，ECT后15分钟fQRS-T角的增加在ECT后24小时显着降低（p=0.031）。同时,基线和24小时fQRS-T角之间没有显着差异（p=0.154）。
■在我们的研究中，ECT后15分钟观察到fQRS-T角显着增加。然而,24小时后fQRS-T角恢复正常.我们的发现可能表明，根据fQRS-T角度，ECT对心血管事件的风险没有永久性副作用。
