关键词: Anti-coagulants Deep venous thrombosis Enoxaparin Human immunodeficiency virus (HIV)

来  源:   DOI:10.18502/ijhoscr.v18i2.15379   PDF(Pubmed)

Abstract:
Patients with human immunodeficiency virus (HIV) infection have an increased likelihood of venous thromboembolism (VTE) owing to factors such as acquired protein C and S deficiency, antiphospholipid antibody syndrome, and heightened levels of pro-inflammatory cytokines. This case report highlights an exceptionally uncommon occurrence of deep venous thrombosis in an HIV-infected patient receiving a therapeutic dose of enoxaparin. This underscores the need for cautious consideration of the risk of VTE in HIV-infected individuals, even with preventive or therapeutic anticoagulant treatment. Further research is recommended to investigate HIV as a potential risk factor of prophylactic anticoagulation.
摘要:
人类免疫缺陷病毒(HIV)感染的患者由于诸如获得性蛋白C和S缺陷等因素,静脉血栓栓塞(VTE)的可能性增加。抗磷脂抗体综合征,和促炎细胞因子水平升高。此病例报告强调了在接受治疗剂量依诺肝素的HIV感染患者中,深静脉血栓形成的异常罕见发生。这强调需要谨慎考虑艾滋病毒感染者的VTE风险,即使是预防性或治疗性抗凝治疗。建议进一步研究HIV作为预防性抗凝的潜在危险因素。
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