关键词: DMT ayahuasca ceremony harmala alkaloids psychedelic

来  源:   DOI:10.1002/pcn5.146   PDF(Pubmed)

Abstract:
Ayahuasca is a psychedelic plant brew originating from the Amazon rainforest. It is formed from two basic components, the Banisteriopsis caapi vine and a plant containing the potent psychedelic dimethyltryptamine (DMT), usually Psychotria viridis. Here we review the history of ayahuasca and describe recent work on its pharmacology, phenomenological responses, and clinical applications. There has been a significant increase in interest in ayahuasca since the turn of the millennium. Anecdotal evidence varies significantly, ranging from evangelical accounts to horror stories involving physical and psychological harm. The effects of the brew on personality and mental health outcomes are discussed in this review. Furthermore, phenomenological analyses of the ayahuasca experience are explored. Ayahuasca is a promising psychedelic agent that warrants greater empirical attention regarding its basic neurochemical mechanisms of action and potential therapeutic application.
摘要:
Ayahuasca是一种源自亚马逊雨林的迷幻植物酿造。它由两个基本组成部分组成,Banisteriopsiscaapivine和一种含有强效迷幻二甲基色胺(DMT)的植物,通常是精神病患者。在这里,我们回顾了ayahuasca的历史,并描述了其药理学的最新工作,现象学反应,和临床应用。自千年之交以来,对ayahuasca的兴趣显着增加。轶事证据差异很大,范围从福音的帐户到涉及身体和心理伤害的恐怖故事。本文讨论了啤酒对人格和心理健康结果的影响。此外,探索了ayahuasca经验的现象学分析。Ayahuasca是一种有前途的迷幻剂,值得对其基本的神经化学作用机制和潜在的治疗应用给予更多的经验关注。
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