PDF(Pubmed)
Abstract：
UNASSIGNED: Idiopathic basal ganglia calcification (IBGC), also known as Farh\'s disease, is a rare neurodegenerative disorder characterized by calcification of the basal ganglia and other brain regions. This disease usually occurs in middle-aged patients and presents with various neurological and psychiatric symptoms. The exact prevalence is unknown; however, population genomic data analysis suggests a prevalence of at least 4.5/10,000 to 3.3/1000, indicating that the disease is more common than previously thought and remains underdiagnosed.
UNASSIGNED: We report the case of a middle-aged Japanese man who attempted suicide twice because of obsessive-compulsive ideation caused by trivial triggers. The patient\'s psychiatric symptoms resolved relatively quickly after hospitalization, and imaging and genetic testing led to a diagnosis of IBGC.
UNASSIGNED: This case report illustrates the importance of including IBGC in the differential diagnosis of psychiatric symptoms that initially develop in middle-aged patients.
UNASSIGNED: We report the case of a middle-aged Japanese man who attempted suicide twice because of obsessive-compulsive ideation caused by trivial triggers. The patient\'s psychiatric symptoms resolved relatively quickly after hospitalization, and imaging and genetic testing led to a diagnosis of IBGC.
UNASSIGNED: This case report illustrates the importance of including IBGC in the differential diagnosis of psychiatric symptoms that initially develop in middle-aged patients.
摘要：
■特发性基底节钙化（IBGC），也被称为法氏病,是一种罕见的神经退行性疾病，其特征是基底神经节和其他大脑区域钙化。这种疾病通常发生在中年患者中，并表现为各种神经和精神症状。确切的患病率未知；然而，人群基因组数据分析显示,该疾病的患病率至少为4.5/10,000~3.3/1000,这表明该疾病比以前认为的更常见,并且仍未被诊断.
■我们报道了一个日本中年男子的案例，该男子由于琐碎的触发因素引起的强迫症而两次自杀。患者的精神症状在住院后相对较快地缓解，影像学和基因检测导致IBGC的诊断。
■本病例报告说明了将IBGC纳入中年患者最初出现的精神症状的鉴别诊断中的重要性。
■我们报道了一个日本中年男子的案例，该男子由于琐碎的触发因素引起的强迫症而两次自杀。患者的精神症状在住院后相对较快地缓解，影像学和基因检测导致IBGC的诊断。
■本病例报告说明了将IBGC纳入中年患者最初出现的精神症状的鉴别诊断中的重要性。
