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Abstract：
UNASSIGNED: Haemodynamic alterations of the retrobulbar circulation are sequelae of untreated, long-standing hypertension. Early evaluation of the retrobulbar blood flow is very crucial to prevent irreversible ocular complications. The objective of this study was to evaluate the differences in central retinal artery (CRA) and ophthalmic artery (OA) haemodynamics in adult hypertensive and non-hypertensive subjects.
UNASSIGNED: This prospective, comparative cross-sectional study was conducted among 63 hypertensives and 75 normotensive controls. Using Doppler ultrasonography, the CRA and OA Doppler velocimetry parameters among cases and controls were evaluated and analysed.
UNASSIGNED: The CRA Peak Systolic Velocity (PSV) and End-diastolic velocity (EDV) was 7.54 ± 2.60cm/s and 2.99 ± 1.15cm/s (p<0.001) in hypertensives but 10.8 ± 2.51cm/s and 4.50 ± 1.25cm/s) p<0.001 in controls. The systolic/diastolic ratio (S/D) in cases was 2.64 ± 0.75 and 2.44 ± 0.38 p=0.045 in controls. The CRA\'s Pulsatility Index (PI) between cases and controls was not statistically significant, p =0.082. Furthermore, the CRA\'s PSV, PI, Resistivity index (RI) and S/D, were higher among subjects with stage 1 compared to stage 2 hypertension (p=0.004; p=0.027; p<0.001 and p=0.001 respectively). The OA mean EDV in hypertensives was 4.57 ± 1.97 and in controls= 5.31 ± 1.79 (p=0.022), while the OA mean RI and Peak Ratio, p=0.009 and 0.003, respectively, were higher in stage 1 hypertension.
UNASSIGNED: The Central retinal and ophthalmic artery blood flow parameters were significantly lower among hypertensive cases. Also, hypertensive stage 2 cases had significantly lower blood flow and vascular impedance parameters in the CRA and both Central retinal and ophthalmic artery, respectively.
UNASSIGNED: This prospective, comparative cross-sectional study was conducted among 63 hypertensives and 75 normotensive controls. Using Doppler ultrasonography, the CRA and OA Doppler velocimetry parameters among cases and controls were evaluated and analysed.
UNASSIGNED: The CRA Peak Systolic Velocity (PSV) and End-diastolic velocity (EDV) was 7.54 ± 2.60cm/s and 2.99 ± 1.15cm/s (p<0.001) in hypertensives but 10.8 ± 2.51cm/s and 4.50 ± 1.25cm/s) p<0.001 in controls. The systolic/diastolic ratio (S/D) in cases was 2.64 ± 0.75 and 2.44 ± 0.38 p=0.045 in controls. The CRA\'s Pulsatility Index (PI) between cases and controls was not statistically significant, p =0.082. Furthermore, the CRA\'s PSV, PI, Resistivity index (RI) and S/D, were higher among subjects with stage 1 compared to stage 2 hypertension (p=0.004; p=0.027; p<0.001 and p=0.001 respectively). The OA mean EDV in hypertensives was 4.57 ± 1.97 and in controls= 5.31 ± 1.79 (p=0.022), while the OA mean RI and Peak Ratio, p=0.009 and 0.003, respectively, were higher in stage 1 hypertension.
UNASSIGNED: The Central retinal and ophthalmic artery blood flow parameters were significantly lower among hypertensive cases. Also, hypertensive stage 2 cases had significantly lower blood flow and vascular impedance parameters in the CRA and both Central retinal and ophthalmic artery, respectively.
摘要：
■球后循环的血流动力学改变是未经治疗的后遗症，长期高血压.早期评估球后血流对于预防不可逆的眼部并发症非常关键。这项研究的目的是评估成年高血压和非高血压受试者的视网膜中央动脉（CRA）和眼动脉（OA）血流动力学的差异。
■这个前景，在63名高血压患者和75名血压正常对照中进行了横断面比较研究.使用多普勒超声检查，对病例和对照组的CRA和OA多普勒测速参数进行评估和分析。
■高血压患者的CRA收缩压峰值速度（PSV）和舒张末期速度（EDV）分别为7.54±2.60cm/s和2.99±1.15cm/s（p<0.001），而对照组为10.8±2.51cm/s和4.50±1.25cm/s）p<0.001。对照组的收缩压/舒张压比（S/D）为2.64±0.75和2.44±0.38p=0.045。病例和对照组之间的CRA搏动指数（PI）没有统计学意义，p=0.082。此外，CRA的PSV，PI,电阻率指数（RI）和S/D，与第2阶段高血压相比，第1阶段高血压的受试者更高（p=0.004;p=0.027;p分别<0.001和p=0.001）。高血压患者的OA平均EDV为4.57±1.97，对照组为5.31±1.79（p=0.022），而OA是指RI和峰比，p分别为0.009和0.003，在1期高血压中较高。
■在高血压病例中，视网膜中央和眼动脉血流参数明显较低。此外，2期高血压患者CRA、视网膜中央动脉和眼动脉的血流量和血管阻抗参数明显降低，分别。
■这个前景，在63名高血压患者和75名血压正常对照中进行了横断面比较研究.使用多普勒超声检查，对病例和对照组的CRA和OA多普勒测速参数进行评估和分析。
■高血压患者的CRA收缩压峰值速度（PSV）和舒张末期速度（EDV）分别为7.54±2.60cm/s和2.99±1.15cm/s（p<0.001），而对照组为10.8±2.51cm/s和4.50±1.25cm/s）p<0.001。对照组的收缩压/舒张压比（S/D）为2.64±0.75和2.44±0.38p=0.045。病例和对照组之间的CRA搏动指数（PI）没有统计学意义，p=0.082。此外，CRA的PSV，PI,电阻率指数（RI）和S/D，与第2阶段高血压相比，第1阶段高血压的受试者更高（p=0.004;p=0.027;p分别<0.001和p=0.001）。高血压患者的OA平均EDV为4.57±1.97，对照组为5.31±1.79（p=0.022），而OA是指RI和峰比，p分别为0.009和0.003，在1期高血压中较高。
■在高血压病例中，视网膜中央和眼动脉血流参数明显较低。此外，2期高血压患者CRA、视网膜中央动脉和眼动脉的血流量和血管阻抗参数明显降低，分别。
