Abstract：
Several brainstem, subcortical and cortical areas are involved in the generation of rapid eye movement (REM) sleep. The alteration of these structures as a result of a neurodegenerative process may therefore lead to REM sleep anomalies. REM sleep behaviour disorder is associated with nightmares, dream-enacting behaviours and increased electromyographic activity in REM sleep. Its isolated form is a harbinger of synucleinopathies such as Parkinson\'s disease or dementia with Lewy bodies, and neuroprotective interventions are advocated. This link might also be present in patients taking antidepressants, with post-traumatic stress disorder, or with a history of repeated traumatic head injury. REM sleep likely contributes to normal memory processes. Its alteration has also been proposed to be part of the neuropathological changes occurring in Alzheimer\'s disease.
摘要：
几个脑干，皮质下和皮质区域参与快速眼动（REM）睡眠的产生。作为神经退行性过程的结果的这些结构的改变可能因此导致REM睡眠异常。REM睡眠行为障碍与噩梦有关，REM睡眠中的做梦行为和肌电图活动增加。它的分离形式是突触核蛋白病的先兆，如帕金森病或路易体痴呆，并提倡神经保护干预措施。这种联系也可能存在于服用抗抑郁药的患者中，患有创伤后应激障碍，或者有反复的头部外伤史.REM睡眠可能有助于正常的记忆过程。它的改变也被认为是阿尔茨海默病中发生的神经病理学改变的一部分。
