Abstract：
OBJECTIVE: Eating disorders (EDs) represent a major public health burden. Increasingly, studies suggest mental health (MH) fields are failing to improve the effectiveness of treatments and that alternative models of care must be considered. Precision mental health (PMH) seeks to tailor treatment to individual needs and relies on a comprehensive understanding of the neurobiological and physiological underpinnings of mental illness.
METHODS: In this narrative review, published literature with focus on biological application of PMH strategies for EDs is reviewed and summarised.
RESULTS: A total of 39 articles were retained for the review covering a variety of themes with relevance to PMH. Many studies of biological markers with PMH applicability focused on anorexia nervosa. Although a variety of potential PMH research applications were identified, the review failed to identify any evidence of implementation into routine ED practice.
CONCLUSIONS: Despite the theoretical merit of biological application of PMH in ED treatment, clinical applications for standard practice are lacking. There is a need to invest further in studies that seek to identify biological markers and investigate neurobiological underpinnings of disease in hopes of targeting and developing treatments that can be better tailored to the individualised needs of patients.
METHODS: In this narrative review, published literature with focus on biological application of PMH strategies for EDs is reviewed and summarised.
RESULTS: A total of 39 articles were retained for the review covering a variety of themes with relevance to PMH. Many studies of biological markers with PMH applicability focused on anorexia nervosa. Although a variety of potential PMH research applications were identified, the review failed to identify any evidence of implementation into routine ED practice.
CONCLUSIONS: Despite the theoretical merit of biological application of PMH in ED treatment, clinical applications for standard practice are lacking. There is a need to invest further in studies that seek to identify biological markers and investigate neurobiological underpinnings of disease in hopes of targeting and developing treatments that can be better tailored to the individualised needs of patients.
摘要：
目的：进食障碍（ED）是主要的公共卫生负担。越来越多,研究表明，心理健康（MH）领域未能提高治疗的有效性，必须考虑替代护理模式。精准心理健康（PMH）旨在根据个人需求定制治疗方法，并依赖于对精神疾病的神经生物学和生理基础的全面了解。
方法：在这篇叙述性综述中，回顾并总结了已发表的文献，重点是针对ED的PMH策略的生物学应用。
结果：本综述共保留了39篇文章，涵盖了与PMH相关的各种主题。许多具有PMH适用性的生物标记的研究集中在神经性厌食症上。尽管已经确定了各种潜在的PMH研究应用，审查未能发现任何实施常规ED实践的证据.
结论：尽管PMH在ED治疗中的生物学应用具有理论价值，缺乏标准实践的临床应用。有必要进一步投资于寻求识别生物学标志物和研究疾病的神经生物学基础的研究，以期靶向和开发可以更好地适应患者个性化需求的治疗方法。
方法：在这篇叙述性综述中，回顾并总结了已发表的文献，重点是针对ED的PMH策略的生物学应用。
结果：本综述共保留了39篇文章，涵盖了与PMH相关的各种主题。许多具有PMH适用性的生物标记的研究集中在神经性厌食症上。尽管已经确定了各种潜在的PMH研究应用，审查未能发现任何实施常规ED实践的证据.
结论：尽管PMH在ED治疗中的生物学应用具有理论价值，缺乏标准实践的临床应用。有必要进一步投资于寻求识别生物学标志物和研究疾病的神经生物学基础的研究，以期靶向和开发可以更好地适应患者个性化需求的治疗方法。
