PDF(Pubmed)
Abstract：
The aim of the present study was to examine the growth dynamics of the two ossification centers of the body of sphenoid bone in the human fetus, based on their linear, planar and volumetric parameters. The examinations were carried out on 37 human fetuses of both sexes aged 18-30 weeks of gestation, which had been preserved in 10% neutral formalin solution. Using CT, digital image analysis software, 3D reconstruction and statistical methods, we evaluated the size of the presphenoid and postsphenoid ossification centers. The presphenoid ossification center grew proportionately in sagittal diameter, projection surface area and volume, and logarithmically in transverse diameter. The postsphenoid ossification center increased logarithmically in sagittal diameter, transverse diameter and projection surface area, while its volumetric growth followed proportionately. The numerical findings of the presphenoid and postsphenoid ossification centers may be considered age-specific reference values of potential relevance in monitoring the normal fetal growth and screening for congenital disorders in the fetus. The obtained results may contribute to a better understanding of the growing fetal skeleton, bringing new numerical information regarding its diagnosis and development.
摘要：
本研究的目的是检查人类胎儿蝶骨的两个骨化中心的生长动力学，基于它们的线性，平面和体积参数。对妊娠18-30周的37名男女胎儿进行了检查，保存在10%中性福尔马林溶液中。使用CT,数字图像分析软件,三维重建和统计方法，我们评估了蝶骨前和蝶骨后骨化中心的大小.前类骨化中心在矢状径上成比例地增长，投影表面积和体积，横向直径呈对数。蝶骨后骨化中心矢状径呈对数增大，横向直径和投影表面积，而其体积增长则成比例地跟随。蝶前和蝶骨后骨化中心的数值发现可被认为是监测胎儿正常生长和筛查胎儿先天性疾病的潜在相关性的年龄特异性参考值。获得的结果可能有助于更好地了解胎儿骨骼的生长，为其诊断和发展带来新的数字信息。
