免疫刺激核酸纳米颗粒 (NANP) 增强对金黄色葡萄球菌的保护性成骨细胞和破骨细胞 I 型干扰素应答。
关键词: Cytosolic nucleic acid sensors Nucleic acid nanoparticles (NANPs) Osteoblasts Osteoclasts Staphylococcus aureus Type I interferons
Mesh : Staphylococcus aureus / drug effects immunology Nanoparticles / chemistry Osteoblasts / drug effects metabolism Osteoclasts / drug effects metabolism Animals Nucleic Acids / chemistry pharmacology Staphylococcal Infections / immunology drug therapy Mice Interferon Type I / metabolism Humans Interferon-beta / metabolism Adjuvants, Immunologic / pharmacology
来 源:
DOI:10.1016/j.nano.2024.102762
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