Abstract：
Marine organisms commonly encounter co-stress resulting from the coexistence of microplastics (MPs) and heavy metals pollution in marine environments. Nevertheless, the combined effects and toxicity mechanisms of MPs and heavy metals on marine organisms remain unclear. This study integrated growth, physiological, morphological, and biochemical markers to assess the individual and combined toxicity of polyvinyl chloride MPs (PVC MPs, 1 × 104 particles/L) and copper (Cu, 200 μg/L) on marine jacopever (Sebastes schlegelii). The results revealed that co-exposure to MPs and Cu had a more detrimental impact on jacopever compared to the single-exposure groups, as evidenced by the enhanced growth inhibition, respiratory stress, and hepatotoxicity. This phenomenon may be attributed to PVC MPs accelerating the accumulation of Cu in jacopever liver. Therefore, peroxidation damage occurred in the co-exposed liver and may result in liver dysfunction. These findings contribute valuable insights into the risks associated with the coexistence of MPs and heavy metal pollution in marine ecosystems.
摘要：
海洋生物通常会遇到由于海洋环境中微塑料（MPs）和重金属污染共存而引起的共同压力。然而，MPs和重金属对海洋生物的联合作用和毒性机制尚不清楚.本研究综合生长，生理,形态学,和生化标志物，以评估聚氯乙烯MPs(PVCMPs，1×104颗粒/L）和铜（Cu，200μg/L）在海洋jacopever（Sebastesschlegelii）上。结果表明，与单一暴露组相比，共同暴露于MPs和Cu对jacopever的影响更大，生长抑制增强证明了这一点，呼吸压力,和肝毒性。这种现象可能归因于PVCMPs加速了铜在jacopever肝脏中的积累。因此,过氧化损伤发生在共同暴露的肝脏，并可能导致肝功能障碍。这些发现为海洋生态系统中MP和重金属污染共存的风险提供了宝贵的见解。
