PDF(Pubmed)
Abstract：
Breast sarcoma is a rare but aggressive tumor. There are few case reports in the literature and several aspects of this disease are still not completely comprehended. Therefore, reporting new cases can help to enrich the literature. We report a patient with breast mass and pus secretion from her right breast, misdiagnosed as an abscess and mistreated by antibiotics. The patient was referred for an ultrasound examination and mammography, and a needle biopsy was performed that suggested an aggressive tumor. By the pathologist\'s suggestion, a total mastectomy of the right breast was performed with the excision of sentinel nodes. A pathological examination revealed a high-grade undifferentiated pleomorphic sarcoma (UPS) without vascular or lymph node invasion as the final diagnosis. The patient underwent postoperative chemotherapy and is currently in good condition. This case emphasizes considering this rare tumor when approaching a breast mass. Performing surgery with adequate resection margin can improve the patient\'s prognosis. Some suggested breast UPS cases with lung and brain metastasis would be more aggressive tumors than other breast sarcomas. Total mastectomy with negative margins and free-of-tumor lymph nodes may be the key to improve prognosis in such patients.
摘要：
乳腺肉瘤是一种罕见但侵袭性的肿瘤。文献中很少有病例报道，这种疾病的几个方面仍未完全理解。因此,报告新病例有助于丰富文献。我们报告了一名患者，她的右乳房有乳房肿块和脓液分泌，误诊为脓肿并被抗生素虐待。患者被转诊接受超声检查和乳房X光检查，进行了穿刺活检，提示肿瘤侵袭性。根据病理学家的建议，在切除前哨淋巴结的同时，对右乳房进行了全乳房切除术。病理检查显示高度未分化的多形性肉瘤（UPS），无血管或淋巴结侵犯作为最终诊断。患者接受了术后化疗，目前情况良好。这种情况强调在接近乳房肿块时考虑这种罕见的肿瘤。手术切缘充足,可改善患者预后。一些人认为，与其他乳腺肉瘤相比，具有肺和脑转移的乳腺UPS病例更具侵袭性。具有阴性边缘和无肿瘤淋巴结的全乳房切除术可能是改善此类患者预后的关键。
