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Abstract：
Metaplastic thymoma is a rare biphasic thymic tumor with indolent behavior and recurrent YAP1::MAML2 gene rearrangement. Although the diagnosis of this tumor is usually straightforward based on hematoxylin and eosin (H&E) findings alone, cases with scant spindle-cell (\"pseudosarcomatous stroma\") components can be easily confused with more commonly occurring type A thymoma. We present a case of metaplastic thymoma with a sparse stroma-like spindle-cell component, discussing its histological and immunohistochemical hints and drawing attention to the visual similarity to type A thymoma. This is also the first published case of metaplastic thymoma with associated psoriasis.
摘要：
化生胸腺瘤是一种罕见的双相胸腺肿瘤，表现为惰性和复发性YAP1::MAML2基因重排。虽然这种肿瘤的诊断通常是直接基于苏木精和曙红（H＆E）的发现，梭形细胞（“假肉瘤间质”）成分不足的病例很容易与更常见的A型胸腺瘤混淆。我们介绍了一例具有稀疏基质样梭形细胞成分的化生性胸腺瘤，讨论其组织学和免疫组织化学提示，并提请注意与A型胸腺瘤的视觉相似性。这也是第一例与银屑病相关的化生胸腺瘤。
