Abstract：
BACKGROUND: Esophageal pH-impedance monitoring is a tool for diagnosing gastroesophageal reflux in children. The position of the pH catheter is essential for a reliable reading and the current formulas for calculating catheter insertion length are not completely accurate. The aim of the present study was to develop a new formula for adequate insertion of the pH catheter.
METHODS: A cross-sectional study was conducted on children that underwent pH-impedance monitoring and later radiographic control, to calculate the correct catheter insertion length. The documented variables were age, sex, weight, height, naris to tragus distance, tragus to sternal notch distance, sternal notch to xiphoid process distance, and initial insertion length determined by the Strobel and height interval formulas. A multivariate regression analysis was carried out to predict the final insertion length. Regression ANOVA and Pearson\'s adjusted R-squared tests were performed.
RESULTS: Forty-five pH-impedance studies were carried out, 53% of which were in males. The age and weight variables were not normally distributed. In the initial regression model, the variables that did not significantly correlate with the final insertion length were: sex (P 0.124), length determined by the Strobel or height interval formulas (P 0.078), naris to tragus distance (P 0.905), and tragus to sternal notch distance (P 0.404). The final equation: 5.6 + (height in cm * 0.12) + (sternal notch to xiphoid process distance * 0.57) produced an R2 of 0.93 (P 0.000).
CONCLUSIONS: This formula can be considered a valid option for placement of the pH-impedance monitoring catheter in pediatrics.
METHODS: A cross-sectional study was conducted on children that underwent pH-impedance monitoring and later radiographic control, to calculate the correct catheter insertion length. The documented variables were age, sex, weight, height, naris to tragus distance, tragus to sternal notch distance, sternal notch to xiphoid process distance, and initial insertion length determined by the Strobel and height interval formulas. A multivariate regression analysis was carried out to predict the final insertion length. Regression ANOVA and Pearson\'s adjusted R-squared tests were performed.
RESULTS: Forty-five pH-impedance studies were carried out, 53% of which were in males. The age and weight variables were not normally distributed. In the initial regression model, the variables that did not significantly correlate with the final insertion length were: sex (P 0.124), length determined by the Strobel or height interval formulas (P 0.078), naris to tragus distance (P 0.905), and tragus to sternal notch distance (P 0.404). The final equation: 5.6 + (height in cm * 0.12) + (sternal notch to xiphoid process distance * 0.57) produced an R2 of 0.93 (P 0.000).
CONCLUSIONS: This formula can be considered a valid option for placement of the pH-impedance monitoring catheter in pediatrics.
摘要：
背景：食管pH-阻抗监测是诊断儿童胃食管反流的工具。pH导管的位置对于可靠的读数至关重要，并且用于计算导管插入长度的当前公式并不完全准确。本研究的目的是开发一种用于适当插入pH导管的新配方。
方法：对接受pH-阻抗监测和后来的射线照相控制的儿童进行了横断面研究，计算正确的导管插入长度。记录的变量是年龄，性别,体重,高度,纳里斯到耳屏的距离，耳屏到胸骨切迹的距离,胸骨切迹到剑突的距离，和初始插入长度由Strobel和高度间隔公式确定。进行多元回归分析以预测最终的插入长度。进行回归方差分析和皮尔森调整后的R平方检验。
结果：进行了45项pH-阻抗研究，其中53%为男性。年龄和体重变量不呈正态分布。在初始回归模型中，与最终插入长度没有显着相关的变量是：性别（P0.124），由Strobel或高度间隔公式确定的长度(P0.078)，鼻翼到耳屏距离(P0.905)，耳屏到胸骨切迹距离(P0.404)。最终方程式：5.6（高度，cm*0.12）（胸骨切迹到剑突距离*0.57）产生的R2为0.93（P0.000）。
结论：该公式可被认为是在儿科中放置pH阻抗监测导管的有效选择。
方法：对接受pH-阻抗监测和后来的射线照相控制的儿童进行了横断面研究，计算正确的导管插入长度。记录的变量是年龄，性别,体重,高度,纳里斯到耳屏的距离，耳屏到胸骨切迹的距离,胸骨切迹到剑突的距离，和初始插入长度由Strobel和高度间隔公式确定。进行多元回归分析以预测最终的插入长度。进行回归方差分析和皮尔森调整后的R平方检验。
结果：进行了45项pH-阻抗研究，其中53%为男性。年龄和体重变量不呈正态分布。在初始回归模型中，与最终插入长度没有显着相关的变量是：性别（P0.124），由Strobel或高度间隔公式确定的长度(P0.078)，鼻翼到耳屏距离(P0.905)，耳屏到胸骨切迹距离(P0.404)。最终方程式：5.6（高度，cm*0.12）（胸骨切迹到剑突距离*0.57）产生的R2为0.93（P0.000）。
结论：该公式可被认为是在儿科中放置pH阻抗监测导管的有效选择。
