Mesh : Humans Fluorodeoxyglucose F18 Kidney Transplantation / adverse effects Burkholderia Infections / diagnostic imaging drug therapy Positron Emission Tomography Computed Tomography Burkholderia cepacia Male Fever / etiology Tomography, X-Ray Computed Multimodal Imaging Middle Aged

来  源:   DOI:10.1097/RLU.0000000000005307

Abstract:
UNASSIGNED: Nosocomial Burkholderia cepacia infection in the clinical setting of postrenal transplantation pyrexia of unknown origin and the role of 18 F-FDG PET/CT in treatment optimization in such situation is presented in this report. The consequence of fastidious infection by nosocomial colonizing organisms like B. cepacia can be catastrophic in immunocompromised postrenal transplant individuals causing severe urinary tract infection. In the presented case, following 2 weeks of IV antibiotics, the patient didn\'t show clinical response, and FDG PET scan recognized multifocal infective sites early, likely representing immune reconstitution inflammatory syndrome and timely appropriate and optimal treatment salvaged the renal graft.
摘要:
本报告介绍了未知来源的肾移植后发热的临床环境中的医院伯克霍尔德菌感染以及18F-FDGPET/CT在这种情况下的治疗优化中的作用。在免疫功能低下的肾移植后个体中,像洋葱芽孢杆菌这样的医院定植生物的危重感染的后果可能是灾难性的,导致严重的尿路感染。在本案中,静脉注射抗生素2周后,病人没有表现出临床反应,和FDGPET扫描早期识别多灶性感染部位,可能代表免疫重建炎症综合征,及时适当和最佳的治疗挽救了肾移植物。
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