Abstract：
UNASSIGNED: To compare the ablation techniques\' efficacy of endovenous microwave ablation (EMA) combined with high ligation (HL), foam sclerotherapy (FS) and compression therapy (CT) and endovenous laser ablation (EVLA) combined with HL-FS-CT in the treatment of VLUs.
UNASSIGNED: 301 consecutive patients with VLUs from 2013 to 2022 in a 3200-bed hospital were intervened by EMA combined with HL-FS-CT and EVLA combined with HL-FS-CT were retrospectively compared.
UNASSIGNED: One hundred thirty-four patients underwent EMA+HL-FS-CT and 167 patients underwent EVLA+HL-FS-CT. The primary outcome of the ulcer healing time was 1.45(0.75-1.5) months and 1.86(0.5-2.5) months, respectively, in the two groups (HR for ulcer healing was 1.26, 95% CI [0.96-1.66], p = 0.097). Secondary outcomes included that no significant difference was found in ulcer recurrence and GSV recanalization and complications between the two groups, and the postoperative VCSS and AVVQ were significantly lower than the baseline values in the respective groups (p = 0.0001).
UNASSIGNED: EMA+HL-FS-CT and EVLA+HL-FS-CT are both effective at treating VLUs. Both of the two comprehensive treatments were beneficial to the healing of ulcers, but no evidence showed which one was superior in the ulcer healing time.
UNASSIGNED: 301 consecutive patients with VLUs from 2013 to 2022 in a 3200-bed hospital were intervened by EMA combined with HL-FS-CT and EVLA combined with HL-FS-CT were retrospectively compared.
UNASSIGNED: One hundred thirty-four patients underwent EMA+HL-FS-CT and 167 patients underwent EVLA+HL-FS-CT. The primary outcome of the ulcer healing time was 1.45(0.75-1.5) months and 1.86(0.5-2.5) months, respectively, in the two groups (HR for ulcer healing was 1.26, 95% CI [0.96-1.66], p = 0.097). Secondary outcomes included that no significant difference was found in ulcer recurrence and GSV recanalization and complications between the two groups, and the postoperative VCSS and AVVQ were significantly lower than the baseline values in the respective groups (p = 0.0001).
UNASSIGNED: EMA+HL-FS-CT and EVLA+HL-FS-CT are both effective at treating VLUs. Both of the two comprehensive treatments were beneficial to the healing of ulcers, but no evidence showed which one was superior in the ulcer healing time.
摘要：
■为了比较腔内微波消融（EMA）联合高位结扎（HL）的消融技术的疗效，泡沫硬化疗法（FS）和加压疗法（CT）以及腔内激光消融（EVLA）联合HL-FS-CT治疗VLU。
■对2013年至2022年在一家拥有3200张床位的医院中使用EMA联合HL-FS-CT和EVLA联合HL-FS-CT治疗的301例VLU患者进行回顾性比较。
■134例患者接受了EMA+HL-FS-CT，167例患者接受了EVLA+HL-FS-CT。溃疡愈合时间的主要结果为1.45（0.75-1.5）个月和1.86（0.5-2.5）个月，分别,在两组中（溃疡愈合的HR为1.26，95％CI[0.96-1.66]，p=0.097)。次要结局包括两组间溃疡复发、GSV再通及并发症无显著差异。各组术后VCSS和AVVQ均显著低于基线值(p=0.0001).
■EMA+HL-FS-CT和EVLA+HL-FS-CT均可有效治疗VLU。两种综合治疗均有利于溃疡的愈合，但没有证据表明哪一个在溃疡愈合时间上更优越。
■对2013年至2022年在一家拥有3200张床位的医院中使用EMA联合HL-FS-CT和EVLA联合HL-FS-CT治疗的301例VLU患者进行回顾性比较。
■134例患者接受了EMA+HL-FS-CT，167例患者接受了EVLA+HL-FS-CT。溃疡愈合时间的主要结果为1.45（0.75-1.5）个月和1.86（0.5-2.5）个月，分别,在两组中（溃疡愈合的HR为1.26，95％CI[0.96-1.66]，p=0.097)。次要结局包括两组间溃疡复发、GSV再通及并发症无显著差异。各组术后VCSS和AVVQ均显著低于基线值(p=0.0001).
■EMA+HL-FS-CT和EVLA+HL-FS-CT均可有效治疗VLU。两种综合治疗均有利于溃疡的愈合，但没有证据表明哪一个在溃疡愈合时间上更优越。
