关键词: HMG‐CoA reductase aged 80 and over multimorbidity myopathies statin

Mesh : Humans Female Aged, 80 and over Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects administration & dosage Muscular Diseases / drug therapy chemically induced immunology diagnosis Necrosis Glucocorticoids / administration & dosage therapeutic use Administration, Oral Hydroxymethylglutaryl CoA Reductases / immunology

来  源:   DOI:10.1111/ggi.14922

Abstract:
An 81-year-old woman presented with statin-induced anti-HMGCR immune-mediated necrotizing myopathy. Treatment was successful without complications with a reduced oral steroid dosage from the current consensus for all ages and backgrounds. This case suggests the importance of early diagnosis and the possibility of steroid dosage adjustment considering the patient\'s age, disease severity, and comorbidities.
摘要:
一名81岁女性出现他汀类药物诱导的抗HMGCR免疫介导的坏死性肌病。从目前所有年龄和背景的共识来看,通过减少口服类固醇剂量,治疗是成功的,没有并发症。这种情况表明早期诊断的重要性和考虑患者年龄的类固醇剂量调整的可能性,疾病严重程度,和合并症。
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