PDF(Pubmed)
Abstract：
BACKGROUND: This paper reports the first case of basaloid squamous cell carcinoma clinically and radiologically masquerading as a head and neck paraganglioma.
METHODS: A 66-year-old Sinhalese male with unilateral hearing impairment and 7th-12th (excluding 11th) cranial nerve palsies was diagnosed radiologically with a head and neck paraganglioma by magnetic resonance imaging of the brain, which revealed a hypointense and hyperintense punctate mass centered at the jugular fossa with intracranial extension. The ascending pharyngeal artery, recognized as the major feeder, was embolized by percutaneous embolization following digital subtraction angiography. Gross total resection of the tumor was followed by an uneventful postoperative recovery. Combined immunohistochemistry and histopathological morphology revealed a basaloid squamous cell carcinoma, following which the patient completed radiotherapy and is at 3-month follow-up currently.
CONCLUSIONS: This case report discusses the diagnostic pitfalls and management challenges of this rare entity on the basis of prior evidence, as well as a literature review and clinical and surgical analysis.
METHODS: A 66-year-old Sinhalese male with unilateral hearing impairment and 7th-12th (excluding 11th) cranial nerve palsies was diagnosed radiologically with a head and neck paraganglioma by magnetic resonance imaging of the brain, which revealed a hypointense and hyperintense punctate mass centered at the jugular fossa with intracranial extension. The ascending pharyngeal artery, recognized as the major feeder, was embolized by percutaneous embolization following digital subtraction angiography. Gross total resection of the tumor was followed by an uneventful postoperative recovery. Combined immunohistochemistry and histopathological morphology revealed a basaloid squamous cell carcinoma, following which the patient completed radiotherapy and is at 3-month follow-up currently.
CONCLUSIONS: This case report discusses the diagnostic pitfalls and management challenges of this rare entity on the basis of prior evidence, as well as a literature review and clinical and surgical analysis.
摘要：
背景：本文报道了首例临床和放射学上伪装成头颈部副神经节瘤的基底细胞样鳞状细胞癌。
方法:一名66岁男性僧伽罗人,单侧听力障碍,第7-12(不包括第11)颅神经麻痹,经脑部磁共振成像放射学诊断为头颈部副神经节瘤,显示以颈静脉窝为中心的低信号和高强度点状肿块，颅内延伸。咽升动脉,被认为是主要的喂食器，数字减影血管造影后通过经皮栓塞栓塞栓塞。肿瘤完全切除后，术后恢复顺利。联合免疫组织化学和组织病理学形态显示基底细胞样鳞状细胞癌，随后患者完成放疗，目前正在进行3个月的随访。
结论：本病例报告根据先前的证据讨论了这种罕见实体的诊断缺陷和管理挑战，以及文献回顾和临床和手术分析。
方法:一名66岁男性僧伽罗人,单侧听力障碍,第7-12(不包括第11)颅神经麻痹,经脑部磁共振成像放射学诊断为头颈部副神经节瘤,显示以颈静脉窝为中心的低信号和高强度点状肿块，颅内延伸。咽升动脉,被认为是主要的喂食器，数字减影血管造影后通过经皮栓塞栓塞栓塞。肿瘤完全切除后，术后恢复顺利。联合免疫组织化学和组织病理学形态显示基底细胞样鳞状细胞癌，随后患者完成放疗，目前正在进行3个月的随访。
结论：本病例报告根据先前的证据讨论了这种罕见实体的诊断缺陷和管理挑战，以及文献回顾和临床和手术分析。
