关键词: Dysphagia Immune Nutrition Pneumonia Respiratory dysfunction Spinal cord injury

Mesh : Humans Spinal Cord Injuries / complications Nutritional Status Male Female Middle Aged Pneumonia / etiology Adult Retrospective Studies Risk Factors Aged Cervical Cord / injuries

来  源:   DOI:10.1038/s41598-024-64121-5   PDF(Pubmed)

Abstract:
Pneumonia after cervical spinal cord injury (CSCI) is a common and serious complication; however, its nutrition-related etiology has not yet been elucidated. This study aimed to elucidate the effects of nutritional factors on pneumonia after CSCI. Patients with acute traumatic CSCI who were admitted within 3 days after injury and followed up for at least 3 months were retrospectively examined. Occurrence of pneumonia, nutritional status, severity of dysphagia, vital capacity, use of respirators, and motor scores for paralysis were evaluated. Of 182 patients included in this study, 33 (18%) developed pneumonia. Multiple logistic regression analysis revealed that low nutritional status, severe paralysis, and low vital capacity were significant risk factors for pneumonia. The severity of paralysis, respiratory dysfunction, and poor nutritional status can affect the occurrence of pneumonia after CSCI. In addition to respiratory management, nutritional assessment and intervention may play key roles in preventing pneumonia associated with spinal cord injury-induced immune depression. Nutritional care should be provided as soon as possible when the nutritional status of a patient worsens after an injury.
摘要:
颈脊髓损伤(CSCI)后肺炎是一种常见且严重的并发症,其营养相关病因尚未阐明。本研究旨在阐明营养因素对CSCI后肺炎的影响。对伤后3天内入院并随访至少3个月的急性创伤性CSCI患者进行回顾性检查。肺炎的发生,营养状况,吞咽困难的严重程度,肺活量,使用呼吸器,并评估瘫痪的运动评分。在这项研究中纳入的182名患者中,33(18%)发展为肺炎。多因素logistic回归分析显示,低营养状况,严重瘫痪,低肺活量是肺炎的重要危险因素。瘫痪的严重程度,呼吸功能障碍,营养状况差可影响CSCI后肺炎的发生。除了呼吸管理,营养评估和干预可能在预防脊髓损伤引起的免疫抑制相关肺炎中起关键作用.当患者受伤后营养状况恶化时,应尽快提供营养护理。
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