Abstract：
UNASSIGNED: Feline aortic thromboembolism (FATE) is commonly encountered in clinical medicine, especially in emergency situations. This often devastating syndrome usually develops secondarily to severe heart disease, and has short- and long-term consequences.
UNASSIGNED: The clinical presentation of FATE is consistent with peripheral ischemic neuropathy, usually in both pelvic limbs. Diagnosis is relatively straightforward, but can be assisted with Doppler ultrasound, point-of-care ultrasound or infrared thermal imaging.
UNASSIGNED: Interpretation of survival rates in cats with FATE has been hampered by historically high admission euthanasia, but recent studies suggest a survival rate with supportive care of 30-40%. Moreover, with advances in post-FATE thromboprophylaxis, median survival times of over 1 year are being achieved. Future directions include use of thrombolytic agents and treatment of common FATE sequelae such as acute kidney injury and reperfusion injury.
UNASSIGNED: This article, aimed at small animal veterinarians, including emergency practitioners, reviews key aspects of the clinical presentation, diagnosis and treatment options for FATE, with a view to guiding client and veterinarian decision-making. Three case studies are included to illustrate the practical application of information presented in the review.
UNASSIGNED: There are limited prospective studies on FATE, although the recent literature reflects a resurgence in clinical research interest in the past few years. Advances in FATE treatment will benefit many cats and it is important that research efforts continue to identify appropriate treatment modalities.
UNASSIGNED: The clinical presentation of FATE is consistent with peripheral ischemic neuropathy, usually in both pelvic limbs. Diagnosis is relatively straightforward, but can be assisted with Doppler ultrasound, point-of-care ultrasound or infrared thermal imaging.
UNASSIGNED: Interpretation of survival rates in cats with FATE has been hampered by historically high admission euthanasia, but recent studies suggest a survival rate with supportive care of 30-40%. Moreover, with advances in post-FATE thromboprophylaxis, median survival times of over 1 year are being achieved. Future directions include use of thrombolytic agents and treatment of common FATE sequelae such as acute kidney injury and reperfusion injury.
UNASSIGNED: This article, aimed at small animal veterinarians, including emergency practitioners, reviews key aspects of the clinical presentation, diagnosis and treatment options for FATE, with a view to guiding client and veterinarian decision-making. Three case studies are included to illustrate the practical application of information presented in the review.
UNASSIGNED: There are limited prospective studies on FATE, although the recent literature reflects a resurgence in clinical research interest in the past few years. Advances in FATE treatment will benefit many cats and it is important that research efforts continue to identify appropriate treatment modalities.
摘要：
■猫主动脉血栓栓塞症（FATE）是临床医学中常见的，尤其是在紧急情况下。这种通常具有破坏性的综合征通常继发于严重的心脏病，并有短期和长期的后果。
■FATE的临床表现与周围缺血性神经病一致，通常在骨盆四肢。诊断相对简单，但可以用多普勒超声辅助，护理点超声或红外热成像。
■对有命运的猫的存活率的解释一直受到历史上较高的安乐死的阻碍，但最近的研究表明，支持治疗的生存率为30-40%。此外，随着命运后血栓预防的进展，中位生存时间超过1年。未来的方向包括使用溶栓剂和治疗常见的FATE后遗症，例如急性肾损伤和再灌注损伤。
■本文,针对小动物兽医，包括急救人员,回顾临床表现的关键方面，命运的诊断和治疗选择，以指导客户和兽医决策。包括三个案例研究，以说明审查中提供的信息的实际应用。
■关于命运的前瞻性研究有限，尽管最近的文献反映了过去几年临床研究兴趣的复苏。FATE治疗的进展将使许多猫受益，重要的是研究努力继续确定适当的治疗方式。
■FATE的临床表现与周围缺血性神经病一致，通常在骨盆四肢。诊断相对简单，但可以用多普勒超声辅助，护理点超声或红外热成像。
■对有命运的猫的存活率的解释一直受到历史上较高的安乐死的阻碍，但最近的研究表明，支持治疗的生存率为30-40%。此外，随着命运后血栓预防的进展，中位生存时间超过1年。未来的方向包括使用溶栓剂和治疗常见的FATE后遗症，例如急性肾损伤和再灌注损伤。
■本文,针对小动物兽医，包括急救人员,回顾临床表现的关键方面，命运的诊断和治疗选择，以指导客户和兽医决策。包括三个案例研究，以说明审查中提供的信息的实际应用。
■关于命运的前瞻性研究有限，尽管最近的文献反映了过去几年临床研究兴趣的复苏。FATE治疗的进展将使许多猫受益，重要的是研究努力继续确定适当的治疗方式。
