Abstract：
OBJECTIVE: Sagittal synostosis is the most common isolated craniosynostosis. Surgical treatment of this synostosis has been extensively described in the global literature, with promising outcomes when it is performed in the first 12 months of life. However, in some cases, patients older than 12 months arrive at the craniofacial center with this synostosis. A comprehensive study on efficacy and perioperative outcomes has yet to be fully explored in this population. This systematic review and meta-analysis aimed to assess the available evidence of surgical outcomes for the treatment of sagittal synostosis among older patients to analyze the efficacy and safety of synostosis surgery in this unique population.
METHODS: PubMed, Embase, and Scopus were searched for studies published from inception to March 2024 reporting surgical outcomes of synostosis surgery in older patients (> 12 months) with isolated sagittal synostosis. The main outcome was the reoperation rate, with secondary endpoints including transfusion rates, aesthetic outcomes, and surgical complications.
RESULTS: Nine studies were included in the final analysis. The pooled proportion of the reoperation rate was 1%. The rate of excellent aesthetic results was 95%. The need for transfusion associated with the procedures was 86%, and finally, surgical complications attained a pooled ratio of 2%, indicating minimal morbidity associated with the surgical repair.
CONCLUSIONS: Sagittal synostosis surgery is a safe and effective procedure to perform in older patients; this meta-analysis suggests that open surgery confers a significant rate of excellent aesthetic results with a low reoperation rate and minimal complications associated with the intervention. Future research with direct comparisons among different techniques will validate the findings of this study, which will all contribute to the rigor of synostosis management.
METHODS: PubMed, Embase, and Scopus were searched for studies published from inception to March 2024 reporting surgical outcomes of synostosis surgery in older patients (> 12 months) with isolated sagittal synostosis. The main outcome was the reoperation rate, with secondary endpoints including transfusion rates, aesthetic outcomes, and surgical complications.
RESULTS: Nine studies were included in the final analysis. The pooled proportion of the reoperation rate was 1%. The rate of excellent aesthetic results was 95%. The need for transfusion associated with the procedures was 86%, and finally, surgical complications attained a pooled ratio of 2%, indicating minimal morbidity associated with the surgical repair.
CONCLUSIONS: Sagittal synostosis surgery is a safe and effective procedure to perform in older patients; this meta-analysis suggests that open surgery confers a significant rate of excellent aesthetic results with a low reoperation rate and minimal complications associated with the intervention. Future research with direct comparisons among different techniques will validate the findings of this study, which will all contribute to the rigor of synostosis management.
摘要：
目的：矢状面滑膜是最常见的孤立性颅骨滑膜。在全球文献中已经广泛地描述了这种突触的手术治疗。在生命的前12个月进行时，结果有希望。然而,在某些情况下,年龄超过12个月的患者到达颅面中心并伴有这种骨结炎。在该人群中，关于疗效和围手术期结局的综合研究尚未得到充分探索。本系统评价和荟萃分析旨在评估老年患者矢状面滑膜手术治疗结果的现有证据，以分析该独特人群中滑膜手术的疗效和安全性。
方法：PubMed，Embase,我们搜索了Scopus从开始到2024年3月发表的研究报告,这些研究报告了孤立矢状面滑膜的老年患者(>12个月)的滑膜手术的手术结局.主要结果是再手术率，次要终点包括输血率，美学结果，和手术并发症。
结果：九项研究纳入最终分析。再次手术率的合并比例为1%。美学效果优良率为95%。与手术相关的输血需求为86％，最后，手术并发症的合并比例为2%，表明与手术修复相关的发病率最低。
结论：对于老年患者而言，矢状面滑膜手术是一种安全有效的手术方法；这项荟萃分析提示，开放手术具有较低的再手术率和与干预相关的最小并发症，具有显著的美学效果。未来的研究与不同技术之间的直接比较将验证这项研究的结果，这些都将有助于会议管理的严谨性。
方法：PubMed，Embase,我们搜索了Scopus从开始到2024年3月发表的研究报告,这些研究报告了孤立矢状面滑膜的老年患者(>12个月)的滑膜手术的手术结局.主要结果是再手术率，次要终点包括输血率，美学结果，和手术并发症。
结果：九项研究纳入最终分析。再次手术率的合并比例为1%。美学效果优良率为95%。与手术相关的输血需求为86％，最后，手术并发症的合并比例为2%，表明与手术修复相关的发病率最低。
结论：对于老年患者而言，矢状面滑膜手术是一种安全有效的手术方法；这项荟萃分析提示，开放手术具有较低的再手术率和与干预相关的最小并发症，具有显著的美学效果。未来的研究与不同技术之间的直接比较将验证这项研究的结果，这些都将有助于会议管理的严谨性。
