PDF(Pubmed)
Abstract：
UNASSIGNED: Enteric glia are essential components of the enteric nervous system. Previously believed to have a passive structural function, mounting evidence now suggests that these cells are indispensable for maintaining gastrointestinal homeostasis and exert pivotal influences on both wellbeing and pathological conditions. This study aimed to investigate the global status, research hotspots, and future directions of enteric glia.
UNASSIGNED: The literature on enteric glia research was acquired from the Web of Science Core Collection. VOSviewer software (v1.6.19) was employed to visually represent co-operation networks among countries, institutions, and authors. The co-occurrence analysis of keywords and co-citation analysis of references were conducted using CiteSpace (v6.1.R6). Simultaneously, cluster analysis and burst detection of keywords and references were performed.
UNASSIGNED: A total of 514 publications from 36 countries were reviewed. The United States was identified as the most influential country. The top-ranked institutions were University of Nantes and Michigan State University. Michel Neunlist was the most cited author. \"Purinergic signaling\" was the largest co-cited reference cluster, while \"enteric glial cells (EGCs)\" was the cluster with the highest number of co-occurring keywords. As the keyword with the highest burst strength, Crohns disease was a hot topic in the early research on enteric glia. The burst detection of keywords revealed that inflammation, intestinal motility, and gut microbiota may be the research frontiers.
UNASSIGNED: This study provides a comprehensive bibliometric analysis of enteric glia research. EGCs have emerged as a crucial link between neurons and immune cells, attracting significant research attention in neurogastroenterology. Their fundamental and translational studies on inflammation, intestinal motility, and gut microbiota may promote the treatment of some gastrointestinal and parenteral disorders.
UNASSIGNED: The literature on enteric glia research was acquired from the Web of Science Core Collection. VOSviewer software (v1.6.19) was employed to visually represent co-operation networks among countries, institutions, and authors. The co-occurrence analysis of keywords and co-citation analysis of references were conducted using CiteSpace (v6.1.R6). Simultaneously, cluster analysis and burst detection of keywords and references were performed.
UNASSIGNED: A total of 514 publications from 36 countries were reviewed. The United States was identified as the most influential country. The top-ranked institutions were University of Nantes and Michigan State University. Michel Neunlist was the most cited author. \"Purinergic signaling\" was the largest co-cited reference cluster, while \"enteric glial cells (EGCs)\" was the cluster with the highest number of co-occurring keywords. As the keyword with the highest burst strength, Crohns disease was a hot topic in the early research on enteric glia. The burst detection of keywords revealed that inflammation, intestinal motility, and gut microbiota may be the research frontiers.
UNASSIGNED: This study provides a comprehensive bibliometric analysis of enteric glia research. EGCs have emerged as a crucial link between neurons and immune cells, attracting significant research attention in neurogastroenterology. Their fundamental and translational studies on inflammation, intestinal motility, and gut microbiota may promote the treatment of some gastrointestinal and parenteral disorders.
摘要：
■肠神经胶质是肠神经系统的重要组成部分。以前被认为具有被动结构功能，现在越来越多的证据表明，这些细胞对于维持胃肠稳态是不可缺少的，并且对健康和病理状况都有重要的影响。本研究旨在调查全球现状，研究热点,肠胶质细胞的未来发展方向。
■有关肠神经胶质研究的文献来自WebofScienceCoreCollection。VOSviewer软件（v1.6.19）用于直观地表示国家之间的合作网络，机构,和作者。使用CiteSpace（v6.1。R6).同时,对关键词和参考文献进行聚类分析和突发检测。
■共审查了来自36个国家的514种出版物。美国被认为是最具影响力的国家。排名最高的机构是南特大学和密歇根州立大学。MichelNeunlist是被引用最多的作者。“嘌呤能信号”是最大的共同引用参考簇，而“肠胶质细胞（EGCs）”是同时出现关键词数量最多的簇。作为爆发强度最高的关键词，克罗恩斯病是早期肠胶质细胞研究的热点。对关键词的突发检测显示炎症，肠动力，和肠道微生物群可能是研究的前沿。
■这项研究提供了肠神经胶质研究的全面文献计量学分析。EGCs已经成为神经元和免疫细胞之间的关键纽带，在神经胃肠病学中引起了重要的研究关注。他们对炎症的基础和转化研究，肠动力，和肠道微生物群可能促进一些胃肠道和肠胃外疾病的治疗。
■有关肠神经胶质研究的文献来自WebofScienceCoreCollection。VOSviewer软件（v1.6.19）用于直观地表示国家之间的合作网络，机构,和作者。使用CiteSpace（v6.1。R6).同时,对关键词和参考文献进行聚类分析和突发检测。
■共审查了来自36个国家的514种出版物。美国被认为是最具影响力的国家。排名最高的机构是南特大学和密歇根州立大学。MichelNeunlist是被引用最多的作者。“嘌呤能信号”是最大的共同引用参考簇，而“肠胶质细胞（EGCs）”是同时出现关键词数量最多的簇。作为爆发强度最高的关键词，克罗恩斯病是早期肠胶质细胞研究的热点。对关键词的突发检测显示炎症，肠动力，和肠道微生物群可能是研究的前沿。
■这项研究提供了肠神经胶质研究的全面文献计量学分析。EGCs已经成为神经元和免疫细胞之间的关键纽带，在神经胃肠病学中引起了重要的研究关注。他们对炎症的基础和转化研究，肠动力，和肠道微生物群可能促进一些胃肠道和肠胃外疾病的治疗。
