PDF(Pubmed)
Abstract：
Scurvy, a condition caused by vitamin C deficiency, is characterized by a syndrome of multisystem disorder due to defective collagen production and antioxidative function. This condition is infrequent in this modern era; thus, it is often not within the list of differential diagnoses. The broad clinical picture is generally overlooked as other systemic illnesses, resulting in an extensive investigation that delays the diagnosis. Herein, we report a case of an 8-year-old boy with underlying autism spectrum disorder who presented with lower limb pain and other constitutional symptoms. Examination revealed multiple hyperpigmented scars over the upper and lower limbs and gingival hyperpigmentation. With history of picky eating habits and clinical symptoms supported by radiographic findings, scurvy was suspected and subsequently confirmed based on a low level of ascorbic acid. With vitamin C supplementation and proper nutritional support, the patient recovered well.
摘要：
镰刀,维生素C缺乏引起的疾病,由于胶原蛋白产生和抗氧化功能缺陷，其特征是多系统疾病综合征。这种情况在这个现代时代很少见；因此，它通常不在鉴别诊断范围内.广泛的临床表现通常被忽略为其他系统性疾病，导致广泛的调查延误了诊断。在这里，我们报告了一例8岁的自闭症谱系障碍男孩,他有下肢疼痛和其他全身症状.检查发现上肢和下肢有多个色素沉着过多的疤痕和牙龈色素沉着过多。有挑食习惯的病史和影像学检查结果支持的临床症状，根据低含量的抗坏血酸怀疑并随后证实了镰刀病。补充维生素C和适当的营养支持，病人恢复得很好。
