PDF(Pubmed)
Abstract：
UNASSIGNED: Commonly, the thyroid gland is regarded as an organ with fewer metastatic diseases, and colorectal metastasis to the thyroid (CMT) is rarely reported, especially, with that the clinical sign of thyroid metastasis nidus is the chief complaint. The CMT occurs in advanced colorectal cancer and is associated with poor prognosis and short survival.
UNASSIGNED: In this case, we reported a patient with the sign of neck mass as the first manifestation of CMT. The patient underwent a partial thyroidectomy in June 2019, immunohistochemical findings of thyroid carcinoma suggested the possibility of adenocarcinoma of gastrointestinal tract. The patient underwent a colonoscopy in July 2019 and a colonic mass was found. Pathological examination diagnosed rectal adenocarcinoma. The patient underwent neoadjuvant chemotherapy, surgical treatment, postoperative adjuvant chemotherapy and targeted therapy. The patient died in June 2022.
UNASSIGNED: The metastasis disease would not be ignored at all, when a patient complains at signs of neck mass. Further, the possibility of metastasis cancer should be considered once thyroid nodules occur in patients with colorectal cancer. Even though the biological characteristics and stage of the primary tumor have an important impact on the prognosis, positive standardized treatments can also be helpful.
UNASSIGNED: In this case, we reported a patient with the sign of neck mass as the first manifestation of CMT. The patient underwent a partial thyroidectomy in June 2019, immunohistochemical findings of thyroid carcinoma suggested the possibility of adenocarcinoma of gastrointestinal tract. The patient underwent a colonoscopy in July 2019 and a colonic mass was found. Pathological examination diagnosed rectal adenocarcinoma. The patient underwent neoadjuvant chemotherapy, surgical treatment, postoperative adjuvant chemotherapy and targeted therapy. The patient died in June 2022.
UNASSIGNED: The metastasis disease would not be ignored at all, when a patient complains at signs of neck mass. Further, the possibility of metastasis cancer should be considered once thyroid nodules occur in patients with colorectal cancer. Even though the biological characteristics and stage of the primary tumor have an important impact on the prognosis, positive standardized treatments can also be helpful.
摘要：
■通常，甲状腺被认为是转移性疾病较少的器官，甲状腺结直肠转移（CMT）的报道很少，尤其是,甲状腺转移瘤的临床体征是主诉。CMT发生在晚期结直肠癌中，与预后差和生存期短有关。
■在这种情况下，我们报道了一例以颈部肿块征象为CMT首发表现的患者.患者于2019年6月接受了甲状腺部分切除术，甲状腺癌的免疫组织化学发现提示胃肠道腺癌的可能性。该患者于2019年7月接受了结肠镜检查，发现结肠肿块。病理检查诊断为直肠腺癌。患者接受新辅助化疗,手术治疗,术后辅助化疗和靶向治疗。患者于2022年6月死亡。
■转移疾病根本不会被忽视，当病人抱怨颈部肿块的迹象时。Further,结直肠癌患者一旦发生甲状腺结节，应考虑转移癌的可能性。尽管原发肿瘤的生物学特征和分期对预后有重要影响,积极的标准化治疗也有帮助。
■在这种情况下，我们报道了一例以颈部肿块征象为CMT首发表现的患者.患者于2019年6月接受了甲状腺部分切除术，甲状腺癌的免疫组织化学发现提示胃肠道腺癌的可能性。该患者于2019年7月接受了结肠镜检查，发现结肠肿块。病理检查诊断为直肠腺癌。患者接受新辅助化疗,手术治疗,术后辅助化疗和靶向治疗。患者于2022年6月死亡。
■转移疾病根本不会被忽视，当病人抱怨颈部肿块的迹象时。Further,结直肠癌患者一旦发生甲状腺结节，应考虑转移癌的可能性。尽管原发肿瘤的生物学特征和分期对预后有重要影响,积极的标准化治疗也有帮助。
