PDF(Pubmed)
Abstract：
An analysis of the congenital etiologies of ocular morbidity in children of age 0-12 years is of interest. Hence, this study was conducted over a period of 2 years from Jan 2021- Dec 2023 at RL Jalappa Hospital and Research center that is attached to Sri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, India. Out of 56 patients, 57% were male and 43% were female children. 31 (55%) of mothers belonged to age group between 20-30 years and 24 (43%) between 31-40 years and 1(2%) between 41-50 years. Out of 56 patients, 14 (25%) of them had positive family history. 34 (61%) of them had consanguious marriage. 14 parents (41%) out of 34 are married to second degree consanguinity (brother/sister/grandparent/grandchild) and 20 (59%) belonged to third degree consanguinity (aunt/uncle/niece/nephew/great-grandparent/great-grandchild). Bilateral involvement was seen in 31 (55%). Nasolacrimal duct anomalies were found to be the most common (32%) followed by congenital esotropia (14%). Education, awareness, counseling about risks of consanguinity and other risk factors such as maternal age, infections, medications during pregnancy, vaccination must be a routine practice in healthcare set up. This can significantly reduce morbidity and prevent blindness.
摘要：
对0-12岁儿童眼发病的先天性病因的分析很有意义。因此，这项研究是在2021年1月至2023年12月在RLJalappa医院和研究中心进行的，该中心隶属于SriDevarajUrs医学院，Tamaka,Kolar,卡纳塔克邦,印度。在56名患者中，57%为男性，43%为女性儿童。31名（55％）的母亲属于20-30岁之间的年龄组，而24名（43％）在31-40岁之间，1名（2％）在41-50岁之间。在56名患者中，14(25%)个中有阳性家族史。其中34人（61％）有近亲婚姻。34人中有14位父母（41％）与二级血缘关系（兄弟/姐妹/祖父母/孙子）结婚，有20位父母（59％）与三级血缘关系（姨妈/叔叔/侄女/侄女/侄子/曾祖父/曾孙子女）结婚。31例（55%）出现双边参与。发现鼻泪管异常是最常见的（32％），其次是先天性内斜视（14％）。教育,意识,咨询有关血缘关系的风险和其他风险因素，如产妇年龄，感染,怀孕期间的药物，疫苗接种必须是医疗保健机构的常规做法。这可以显著降低发病率并防止失明。
