Abstract:
Background Cancer is the leading cause of death globally. Information on cancer patterns and survival is essential for the effective planning and implementation of cancer control interventions. Objective This study aimed to identify various factors associated with the survival estimates of common cancers. Methods A community-based ambispective study was conducted in a rural population. Data were collected from individuals diagnosed with cancer or relatives of individuals who died of cancer. The total population covered was 82,983. All cancer cases diagnosed since 2005 and followed until the year 2020 were included. Survival analysis and five-year survival rates were estimated. A Cox proportional hazard model was used. Results A total of 146 cancer patients were included in the study. Five-year survival estimates for breast cancer, head and neck cancer, and GI cancer were 72%, 28%, and 0%, respectively. The median survival time was lowest for GI cancers (1 year), and for head and neck and breast cancers, it was 3 and 6 years, respectively. Multivariate Cox regression was performed, adjusting for age, type of hospital, alcohol use, tobacco use, opium use, gender, treatment sought, GI cancer, frequency of changing hospitals, and frequency of follow-up. After adjustment, changing hospitals ≥3 times, being lost to follow-up, receiving no treatment, tobacco abuse, and the presence of GI cancers were significantly associated with survival estimates. Conclusions The five-year survival estimate for GI cancers was the lowest compared to other cancers. Study participants who were lost to follow-up or who took no treatment were significantly associated with lower survival estimates.
摘要:
背景技术癌症是全球死亡的主要原因。关于癌症模式和生存的信息对于有效规划和实施癌症控制干预措施至关重要。目的本研究旨在确定与常见癌症生存率估计相关的各种因素。方法在农村人群中进行基于社区的综合研究。数据是从被诊断患有癌症的个体或死于癌症的个体的亲属收集的。覆盖的总人口为82,983。包括自2005年以来诊断并随访至2020年的所有癌症病例。评估生存分析和5年生存率。使用Cox比例风险模型。结果共纳入146例癌症患者。乳腺癌的五年生存率估计,头颈癌,胃肠道癌占72%,28%,0%,分别。胃肠道癌症的中位生存时间最低(1年),头颈部和乳腺癌,那是3年和6年,分别。进行多因素Cox回归,调整年龄,医院类型,酒精使用,烟草使用,鸦片的使用,性别,寻求治疗,胃肠道癌,更换医院的频率,和随访频率。调整后,换医院≥3次,失去了后续行动,没有接受治疗,烟草滥用,胃肠道肿瘤的存在与生存率估计显著相关。结论与其他癌症相比,GI癌症的五年生存率估计最低。失去随访或未接受治疗的研究参与者与较低的生存率估计显着相关。