PDF(Pubmed)
Abstract：
Surgical site infections (SSIs) pose a significant clinical challenge, with heightened risks and severe consequences for diabetic patients undergoing surgical procedures. This systematic review aims to synthesize the current evidence on effective prevention strategies for mitigating SSI risk in this vulnerable population. From inception to March 2024, we comprehensively searched multiple electronic databases (PubMed, Medline, Embase, Cochrane Library, CINAHL) to identify relevant studies evaluating SSI prevention strategies in diabetic surgical patients. Our search strategy followed Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, utilizing a combination of keywords and Medical Subject Headings (MeSH) terms related to diabetes, surgical site infections, prevention strategies, and surgical procedures. Inclusion criteria focused on peer-reviewed clinical trials, randomized controlled trials, and meta-analyses published in English. The search yielded three studies meeting the eligibility criteria, subject to data extraction and qualitative synthesis. Key findings highlighted the efficacy of interventions such as optimized perioperative glycemic control, timely prophylactic antibiotic administration, and meticulous preoperative skin antisepsis in reducing SSI rates among diabetic surgical patients. The potential for personalized prevention approaches based on individual patient factors, such as diabetes type and surgical complexity, was explored. This systematic review underscores the importance of a multifaceted, evidence-based approach to SSI prevention in diabetic surgical patients, integrating strategies like glycemic control, antibiotic prophylaxis, and preoperative skin antisepsis. Furthermore, our findings suggest the potential benefits of personalized care pathways tailored to individual patient characteristics. Implementing these interventions requires interdisciplinary collaboration, adaptation to diverse healthcare settings, and patient engagement through culturally sensitive education initiatives. This comprehensive analysis informs clinical practice, fosters patient safety, and contributes to the global efforts to enhance surgical outcomes for this high-risk population.
摘要：
手术部位感染（SSIs）构成了重大的临床挑战，对于接受外科手术的糖尿病患者来说，风险增加，后果严重。本系统综述旨在综合当前有关有效预防策略的证据，以减轻该弱势群体的SSI风险。从成立到2024年3月，我们全面搜索了多个电子数据库(PubMed，Medline,Embase,科克伦图书馆,CINAHL）以确定评估糖尿病手术患者SSI预防策略的相关研究。我们的搜索策略遵循系统评价和荟萃分析(PRISMA)指南的首选报告项目。利用与糖尿病相关的关键词和医学主题词(MeSH)术语的组合，手术部位感染,预防策略,和外科手术。纳入标准侧重于同行评审的临床试验，随机对照试验，以及以英文发表的荟萃分析。搜索产生了三项符合资格标准的研究，进行数据提取和定性综合。关键发现强调了干预措施的有效性，例如优化围手术期血糖控制，及时预防性使用抗生素，术前细致的皮肤防腐可降低糖尿病手术患者的SSI率。基于个体患者因素的个性化预防方法的潜力，比如糖尿病类型和手术复杂性，被探索了。这一系统的审查强调了多方面的重要性，基于证据的方法预防糖尿病手术患者的SSI，整合策略，如血糖控制，抗生素预防，术前皮肤防腐.此外，我们的研究结果表明,针对患者个体特征量身定制的个性化护理路径的潜在益处.实施这些干预措施需要跨学科合作，适应不同的医疗保健环境，通过文化敏感的教育举措和患者参与。这一综合分析为临床实践提供了信息，促进患者安全，并有助于全球努力提高这一高危人群的手术效果。
