关键词: chronic alcoholism long-standing overt ventriculomegaly in adults (lova) macrocephaly neuropsychiatric effects of alcoholism normal pressure hydrocephalus

来  源:   DOI:10.7759/cureus.59973   PDF(Pubmed)

Abstract:
Long-standing overt ventriculomegaly in adults (LOVA) is a kind of chronic hydrocephalus that has been reported to have started in infancy and is characterized by severe ventriculomegaly and macrocephaly. It often manifests clinically in later adulthood. We describe the case of a 34-year-old male patient who had a history of chronic alcoholism and who had been complaining of headaches, disturbed gait, and frequent falls for three months when he arrived in a stupor at the emergency room. Massive ventriculomegaly with Evans\' index of 0.40 was found during a head magnetic resonance imaging (MRI). The MRI results were more severe than the clinical manifestations. He was diagnosed with LOVA and treated with conservative hyperosmolar drugs, neuroprotective agents, and intravenous (IV) thiamine. The patient was discharged and consented to follow-up after a hospital stay of seven days.
摘要:
成人长期明显的脑室肥大(LOVA)是一种慢性脑积水,据报道始于婴儿期,其特征是严重的脑室肥大和大头畸形。它通常在成年后期临床上表现出来。我们描述了一名34岁的男性患者,他有慢性酗酒史,一直抱怨头痛,步态紊乱,当他到达急诊室昏迷时,经常跌倒三个月。在头部磁共振成像(MRI)中发现了巨大的脑室肥大,Evans指数为0.40。MRI结果比临床表现更严重。他被诊断为LOVA,并接受了保守的高渗性药物治疗,神经保护剂,和静脉注射(IV)硫胺素。患者出院,并同意在住院7天后进行随访。
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