关键词: Hydrosalpinx IVF embryo transfer laparoscopy tubal infertility

来  源:   DOI:10.4274/tjod.galenos.2024.36931

Abstract:
UNASSIGNED: Hydrosalpinx impairs the success of in vitro fertilization (IVF) embryo transfer. Various surgical approaches, such as fluid aspiration or isolation of the affected fallopian tubes, have been used to enhance the outcome. This study was conducted to evaluate and compare the efficacy of laparoscopic tubal disconnection (LTD) and hydroscopic tubal electrocoagulation (HTE) for hydrosalpinx before IVF.
UNASSIGNED: After obtaining ethical committee approval, we assessed 112 women who were subfertile due to hydrosalpinx to check their adherence to our selection criteria. Eligible patients were allocated into two groups (LTD vs. HTE). Both groups underwent extensive assessment before the operative procedure. IVF and subsequent embryo transfers were performed in both groups. Live birth and pregnancy rates were evaluated.
UNASSIGNED: Patients who underwent LTD prior to IVF embryo transfer had significantly higher live birth (41%), clinical pregnancy (57%), and chemical pregnancy (61%) rates in the LTD group than in the HTE group (12%, 35%, 41%, respectively). However, we could not find a significant difference between the two groups regarding the miscarriage (17% vs. 28%, p=0.33) and multiple pregnancy (14% vs. 12%, p=0.79) rates. No major complications with HTE were observed, except for a case of uterine perforation, whereas two cases of surgical complications occurred in the LTD group. Additionally, we found a significantly shorter operative time and hospital stay (0.5±0.7 days, p=0.012) in the HTE group.
UNASSIGNED: LTD may be a more effective approach compared with hysteroscopic tubal electrocoagulation for improving birth and pregnancy rates in patients with IVF and hydrosalpinx.
摘要:
输卵管积水会损害体外受精(IVF)胚胎移植的成功。各种手术方法,如液体抽吸或隔离受影响的输卵管,已经被用来提高结果。本研究旨在评估和比较IVF前腹腔镜下输卵管断流术(LTD)和水镜下输卵管电凝术(HTE)治疗输卵管积水的疗效。
获得伦理委员会批准后,我们评估了112名因输卵管积水导致生育力不足的女性,以检查她们是否符合我们的选择标准.符合条件的患者被分为两组(LTD与HTE)。两组在手术前都进行了广泛的评估。两组均进行IVF和随后的胚胎移植。评估了活产和妊娠率。
在IVF胚胎移植之前接受LTD的患者的活产率明显更高(41%),临床妊娠(57%),LTD组的化学妊娠率(61%)高于HTE组(12%,35%,41%,分别)。然而,在流产方面,我们找不到两组之间的显著差异(17%vs.28%,p=0.33)和多胎妊娠(14%vs.12%,p=0.79)费率。未观察到HTE的主要并发症,除了一例子宫穿孔,而LTD组发生2例手术并发症。此外,我们发现手术时间和住院时间明显缩短(0.5±0.7天,HTE组的p=0.012)。
LTD与宫腔镜输卵管电凝术相比,可能是一种更有效的方法,可以改善IVF和输卵管积水患者的分娩率和妊娠率。
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