Abstract：
Eosinophilic gastritis (EoG) is defined as the presence of upper gastrointestinal symptoms combined with histologic findings of > 30 eosinophils/high-power field (eos/hpf) in 5 hpf in any part of the gastric mucosa, except for the secondary causes of gastric eosinophilia. This is the first case report of a serial change in gastric motility in EoG with pyloric stenosis using abdominal ultrasonography. A 56-year-old woman was diagnosed with pyloric stenosis by upper gastrointestinal radiographic examination during a medical checkup. She had nausea and loss of appetite, her gastrointestinal symptom rating scale (GSRS) score was 20, and her F scale score was 20. Esophagogastroduodenoscopy (EGD) demonstrated pyloric stenosis and multiple superficial ulcerations in the antrum. Histopathological findings of gastric biopsy specimens revealed severe eosinophilic infiltration (100 eos/HPF), and the diagnosis was EoG with pyloric stenosis. Before treatment, the gastric anterior wall thickness was 6.3 mm. The gastric motility in EoG was evaluated by intra-abdominal ultrasonography. Ultrasonography showed low motility in the antrum, especially the amplitude and motility index. After 6 months of steroid treatment, her symptoms improved. Her GSRS score was 13, and her F scale score was 19. Histological eosinophilic infiltration decreased to 50 eos/HPF, showing improvement. On ultrasonography, gastric motility also improved and recovered to normal. After 12 months, several examinations confirmed improvement, including gastric motility by ultrasonography.
摘要：
嗜酸性粒细胞性胃炎（EoG）被定义为存在上消化道症状，并在胃粘膜的任何部分的5hpf中出现>30嗜酸性粒细胞/高倍视野（eos/hpf）的组织学发现，除了胃嗜酸性粒细胞增多的次要原因。这是第一例使用腹部超声检查的EoG伴幽门狭窄的胃动力连续变化的病例报告。一名56岁的妇女在体检期间通过上消化道影像学检查被诊断为幽门狭窄。她有恶心和食欲不振,胃肠道症状评定量表(GSRS)评分为20分,F量表评分为20分.食管胃十二指肠镜检查（EGD）显示幽门狭窄和胃窦多发浅表溃疡。胃活检标本的组织病理学发现严重的嗜酸性粒细胞浸润（100eos/HPF），诊断为EoG伴幽门狭窄。治疗前,胃前壁厚度为6.3mm。通过腹内超声检查评估EoG的胃动力。超声检查显示胃窦运动性低，尤其是振幅和运动指数。经过6个月的类固醇治疗，她的症状有所改善。她的GSRS得分为13，F量表得分为19。组织学嗜酸性粒细胞浸润降低至50eos/HPF，显示改进。在超声检查中，胃动力也得到改善并恢复正常。12个月后,几次检查证实有所改善，包括超声检查胃运动。
