Abstract：
Equine bladder neoplasms are rare. This report aimed to describe the clinical signs and treatment of urothelial carcinoma (UC) in a mule. Cystoscopy of a 20-year-old female mule with a one-week history of hematuria and anemia revealed vascular congestion in the mucosa and an intraluminal, pedunculated mass in the dorsal bladder region. Histopathological examination revealed UC. Initial therapy consisted of four weekly cystoscopic guided injections of fluorouracil. At the fourth chemotherapy session, a paler and more friable tumor mass was observed. Consequently, we opted to surgically remove it during cystoscopy. Following mass excision, patient comfort, gross appearance of urine, and the hematocrit returned to normal. Repeat cystoscopy examinations revealed no gross appearance of tumor recurrence 18 months after treatment. Bladder neoplasms clinically resemble urolithiasis and cystitis and should be considered a differential diagnosis in cases of anemia and hematuria.
摘要：
马膀胱肿瘤很少见。本报告旨在描述骡子尿路上皮癌（UC）的临床体征和治疗。对20岁的雌性骡子进行膀胱镜检查，有一周的血尿和贫血病史，发现粘膜和腔内血管充血，背侧膀胱区的带蒂肿块。组织病理学检查显示UC。初始治疗包括每周四次膀胱镜检查引导注射氟尿嘧啶。在第四次化疗会议上，观察到更苍白和更脆弱的肿瘤块。因此,我们选择在膀胱镜检查时手术切除.肿块切除后,患者舒适度,尿液的外观，血细胞比容恢复正常.重复膀胱镜检查显示治疗后18个月未出现肿瘤复发。膀胱肿瘤在临床上类似于尿路结石和膀胱炎，在贫血和血尿的情况下应被视为鉴别诊断。
