Abstract：
BACKGROUND: Cardiovascular diseases (CVD) is the major cause of mortality globally, with increasing evidence suggesting a link between periodontitis, and CVD. This study aims to explore the association between periodontitis and CVD, and the impact of periodontal therapy on cardiovascular health.
METHODS: This review synthesized findings from preclinical and clinical studies, without publication year restrictions, examining periodontitis and CVD through various lenses. Scientific databases were inspected with keywords related to periodontitis and CVD.
RESULTS: The review identifies a substantial association between periodontitis and an increased risk of several CVD, supported by both epidemiological and interventional studies. Results suggest the complexity of the relationship, influenced by factors like the severity of periodontitis and the presence of other systemic conditions. Clinical data indicates that periodontal therapy, particularly non-surgical periodontal therapy, may reduce systemic inflammatory markers and thus may play a role in the primary and secondary prevention of CVD events, highlighting the potential of periodontal therapy to not only maintain oral health but also to modulate cardiovascular risk factors.
CONCLUSIONS: Current evidence supports a significant association between periodontitis and increased cardiovascular risk, promoting integrated healthcare approaches that consider oral health as a key-component of cardiovascular care and wellbeing.
METHODS: This review synthesized findings from preclinical and clinical studies, without publication year restrictions, examining periodontitis and CVD through various lenses. Scientific databases were inspected with keywords related to periodontitis and CVD.
RESULTS: The review identifies a substantial association between periodontitis and an increased risk of several CVD, supported by both epidemiological and interventional studies. Results suggest the complexity of the relationship, influenced by factors like the severity of periodontitis and the presence of other systemic conditions. Clinical data indicates that periodontal therapy, particularly non-surgical periodontal therapy, may reduce systemic inflammatory markers and thus may play a role in the primary and secondary prevention of CVD events, highlighting the potential of periodontal therapy to not only maintain oral health but also to modulate cardiovascular risk factors.
CONCLUSIONS: Current evidence supports a significant association between periodontitis and increased cardiovascular risk, promoting integrated healthcare approaches that consider oral health as a key-component of cardiovascular care and wellbeing.
摘要：
背景：心血管疾病（CVD）是全球死亡的主要原因，越来越多的证据表明牙周炎之间存在联系，和CVD。本研究旨在探讨牙周炎与CVD的关系,以及牙周治疗对心血管健康的影响。
方法：这篇综述综合了临床前和临床研究的结果，没有出版年份限制，通过各种镜片检查牙周炎和CVD。使用与牙周炎和CVD相关的关键词检查了科学数据库。
结果：该综述确定牙周炎与多种心血管疾病风险增加之间存在实质性关联，由流行病学和干预研究支持。结果表明关系的复杂性，受牙周炎严重程度和其他全身性疾病等因素的影响。临床数据表明，牙周治疗，特别是非手术牙周治疗，可能减少全身炎症标志物，因此可能在CVD事件的一级和二级预防中发挥作用，强调牙周治疗不仅可以维持口腔健康，还可以调节心血管危险因素。
结论：目前的证据支持牙周炎与心血管风险增加之间存在显著关联，促进综合医疗保健方法，将口腔健康视为心血管护理和福祉的关键组成部分。
方法：这篇综述综合了临床前和临床研究的结果，没有出版年份限制，通过各种镜片检查牙周炎和CVD。使用与牙周炎和CVD相关的关键词检查了科学数据库。
结果：该综述确定牙周炎与多种心血管疾病风险增加之间存在实质性关联，由流行病学和干预研究支持。结果表明关系的复杂性，受牙周炎严重程度和其他全身性疾病等因素的影响。临床数据表明，牙周治疗，特别是非手术牙周治疗，可能减少全身炎症标志物，因此可能在CVD事件的一级和二级预防中发挥作用，强调牙周治疗不仅可以维持口腔健康，还可以调节心血管危险因素。
结论：目前的证据支持牙周炎与心血管风险增加之间存在显著关联，促进综合医疗保健方法，将口腔健康视为心血管护理和福祉的关键组成部分。
